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| AIHARA, Naoyuki; HORIUCHI, Noriyuki; HIKICHI, Nanase; OCHIAI, Mariko; HOSODA, Yuko; ISHIKAWA, Yoko; SHIMAZAKI, Yoko; OISHI, Koji; 堀内, 雅之. |
| Infectious bursal disease (IBD) is characterized by immunosuppression due to the depletion of lymphocytes in the atrophied bursa of Fabricius (BF). We have sometimes encountered contradictory findings: chickens infected with the vaccine IBD virus (IBDV) strain have sometimes exhibited a highly atrophied BF, but not immunosuppression. In this study, chickens administered vaccine or wild-type strains of IBDV were later vaccinated with the B1 strain of the Newcastle disease virus (NDV). Bursal changes were examined histologically with a focus on the bursal follicle. The immunoreactivity to NDV was also evaluated with the hemagglutination inhibition test. In gross examination, we observed a few chickens with a severely atrophied BF in vaccine... |
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Palavras-chave: Bursal follicle; Infectious bursal disease; Vaccine. |
| Ano: 2015 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4148 |
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