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| Kumbasar,Serkan; Cetin,Nihal; Yapca,Omer Erkan; Sener,Ebru; Isaoglu,Unal; Yilmaz,ehmet; Salman,Suleyman; Aksoy,Ayse Nur; Gul,Mehmet Ali; Suleyman,Halis. |
| In this study, xanthine oxidase (XO), malondialdehyde (MDA), myeloperoxidase (MPO) and glutathione (GSH) levels in the ovarian tissues of rats during the development of ischemia and postischemia-induced reperfusion were investigated, and the effect of ATP on ischemia-reperfusion (I/R) damage was biochemically and histopathologically examined. The results of the biochemical analyses demonstrated that ATP significantly reduced the level of XO and MDA and increased the amount of GSH in both ischemia and I/R-applied ovarian tissue at the doses administered. Furthermore, ATP significantly suppressed the increase in MPO activity that occurred following the application of post ischemia reperfusion in the ovarian tissue. The biochemical results obtained in the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Xanthine oxidase metabolism; Ischemia/reperfusion injury; Antioxidant; Rat. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782014000701257 |
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