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Jeronimo,L. C; Confortim,H. D; Centenaro,L. A; Brancalhão,R. M. C; Pinheiro,P. F. F; Matheus,S. M. M; Torrejais,M. M. |
Protein restriction implies the functional involvement of several systems and organs, including the skeletal muscle, because it is a protein reservoir in the body. This study sought to analyze the morphological and morphometric features of the muscle fibers and neuromuscular junctions (NMJs) of the extensor digitorum longus (EDL) muscle in rats at 365 days of age, submitted to maternal protein restriction during the gestation and lactation periods. Wistar rats were divided into two groups: a Control Group - mothers fed a normal-protein diet (17 % protein) during pregnancy and lactation; and a Restricted Group - mothers fed a low-protein diet (6 % protein) during pregnancy and lactation. The pups were kept with the mother throughout the lactation period (21... |
Tipo: Journal article |
Palavras-chave: Morphology; Morphometry; Protein restriction; Extensor digitorum longus muscle; Rat. |
Ano: 2016 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022016000100057 |
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Torrejais,M. M; Soares,J. C; Matheus,S. M. M; Mello,J. M; Francia-Farje,L. A. D; Jeronimo,L. C; Vicente,E. J. D. |
The structural alterations that occur in the muscle fibers of denervated rat diaphragms were studied. Fifteen adult male albino rats (Rattus norvegicus) with a mean weight of 200 g and about 60 days of age were used. Chronically denervated diaphragms were obtained and the animals were sacrificed after 4, 8 and 12 weeks of denervation. The left antimere of the diaphragm was denervated by sectioning of the phrenic nerve and the right antimere served as control. Each antimere was divided into fragments, which were used for analysis transmission electron microscopy. During the initial phase of denervation (4 weeks), ultrastructural muscle modifications appeared in scattered fibers and in foci along these fibers. Muscle fibers with foci of less dense and... |
Tipo: Journal article |
Palavras-chave: Denervation; Diaphragm; Muscle fiber; Ultrastructural; Rat. |
Ano: 2013 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022013000300025 |
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