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| Faleiro,Mariana Batista Rodrigues; Cintra,Lorena Cardoso; Jesuino,Rosália Santos Amorim; Araújo,Eugênio Gonçalves de; Rocha,Rafael Malagoli; Moura,Veridiana Maria Brianezi Dignani de. |
| ABSTRACT: Gene expression of ErbB1 and ErbB2, and immunostaining of EGFR (Her1) and Her2 (c-erbB-2) were evaluated in this study to ascertain whether these receptors are involved in the evolution of canine premalignant and malignant prostatic lesions, as proliferative inflammatory atrophy (PIA) and prostatic carcinoma (PC). With regards to the intensity of EGFR immunostaining, there was no difference between normal prostatic tissue and tissues with PIA or PC. In relation to Her2 immunostaining, there were differences between normal prostatic tissue and those with PIA and PC, as also differences between prostates with PIA and PC. There was no correlation between EGFR and Her2 immunostaining. ErbB1 gene product was detected in two normal tissue samples, in... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Growth factor receptor; Her1; C-erbB-2; PIA; RT-PCR. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782017001200553 |
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