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Polyethylenimine-Modified Multiwalled Carbon Nanotubes for Plasmid DNA Gene Delivery Nature Precedings
Bo-Zhang Yu; Ji-Fei Ma; Wen-Xin Li.
An efficient molecular delivery technique based on the transporting high-molecular-weight PEI 600K-modified multiwalled carbon nanotubes (PEI 600K-MWCNTs) into cell membranes is reported. The PEI 600K-MWCNTs exhibit low cytotoxicity and its associated plasmid DNA (pDNA) is delivered to cells efficiently, and the green fluorescent protein (GFP) levels up to 18 times higher than that of naked DNA were observed.
Tipo: Manuscript Palavras-chave: Biotechnology; Cancer; Chemistry.
Ano: 2009 URL: http://precedings.nature.com/documents/2753/version/1
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Optical and Electrical Properties of Multi-Walled Carbon Nanotubes Functionalized with Oxadiazole Chromophores Nature Precedings
Bo-Zhang Yu; Ji-Fei Ma; Hu-Lin Li; Ya-Fei Zhang; Wen-Xin La.
Multi-walled carbon nanotubes (MWCNTs) functionalized with oxadiazole chromophores, 2-(4-aminophenyl)-5-naphthyl-1,3,4-oxadiazole (APND) was prepared by an amide linkage. The resultant MWCNTs-APND and APND were characterized by using FT IR, ^1^H NMR, and XRD analysis to give their structural and crystal information, supporting the successful modification. UV-Vis absorption spectrum of MWCNTs-APND was broadened and significantly red-shifted, and its emission peak was narrower than that of APND, which provided direct evidence for reaction of APND with surface of MWCNTs via [pi]-stacking. The electrical properties demonstrated that there was a perfect ohmic behaviour for membrane of APND, and the thin films of MWCNTs-APND had the same nonlinear properties as...
Tipo: Manuscript Palavras-chave: Chemistry.
Ano: 2009 URL: http://precedings.nature.com/documents/2749/version/1
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