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Improved 1-Deoxynojirimycin (DNJ) production in mulberry leaves fermented by microorganism BJM
Jiang,Yun-Gang; Wang,Chu-Yan; Jin,Chao; Jia,Jun-Qiang; Guo,Xijie; Zhang,Guo-Zheng; Gui,Zhong-Zheng.
DNJ, an inhibitor of α-glucosidase, is used to suppress the elevation of postprandial hyperglycemia. In this study, we focus on screening an appropriate microorganism for performing fermentation to improve DNJ content in mulberry leaf. Results showed that Ganoderma lucidum was selected from 8 species and shown to be the most effective in improvement of DNJ production from mulberry leaves through fermentation. Based on single factor and three factor influence level tests by following the Plackett-Burman design, the optimum extraction yield was analyzed by response surface methodology (RSM). The extracted DNJ was determined by reverse-phase high performance liquid chromatograph equipped with fluorescence detector (HPLC-FD). The results of RSM showed that the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Mulberry; DNJ Production; Microorganisms; Fermentation.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822014000200048
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