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	Provedor de dados Biol. Res. (1) Autor CALLEWAERT,GEERT (1) DE SMEDT,HUMBERT (1) KASRI,NAEL NADIF (1) MISSIAEN,LUDWIG (1) PARYS,JAN B. (1) Palavra-chave 4 (1) 5-trisphosphate receptor (1) Calmodulin calcium channels inositol 1 (1) Tipo do documento Journal article (1) Ano 2004 (1) País Chile (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Calmodulin and Calcium-release Channels Biol. Res. KASRI,NAEL NADIF; PARYS,JAN B.; CALLEWAERT,GEERT; MISSIAEN,LUDWIG; DE SMEDT,HUMBERT. Calmodulin (CaM) is a ubiquitous cytosolic protein that plays a critical role in regulating cellular functions by altering the activity of a large number of ion channels. There are many examples for CaM directly mediating the feedback effects of Ca2+ on Ca2+ channels. Recently the molecular mechanisms by which CaM interacts with voltage-gated Ca2+ channels, Ca2+-activated K+ channels and ryanodine receptors have been clarified. CaM plays an important role in regulating these ion channels through lobe-specific Ca2+ detection. CaM seems to behave as a channel subunit. It binds at low [Ca2+] and undergoes conformational changes upon binding of Ca2+, leading to an interaction with another part of the channel to regulate its gating. Here we focus on the... Tipo: Journal article Palavras-chave: Calmodulin calcium channels inositol 1; 4; 5-trisphosphate receptor. Ano: 2004 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602004000400011 Registros recuperados: 1 Primeira ... 1 ... Última

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