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The ingestión of a Nectandra membranácea extract changes the bioavailability of technetium-99m radiobiocomplex in rat organs Biol. Res.
RAMOS FARÍAS MORENO,SILVANA; ARNOBIO,ADRIANO; CARVALH0,JORGE JOSÉ DE; NASCIMENT0,LUCIA; OLIVEIRA TIMOTEO,MARGARETH; OLEJ,BENI; KAZAN ROCHA,EMELY; PEREIRA,MARIO; BERNARDO-FILH0,MARIO; QUERINO DE ARAÚJO CALDAS,LUIZ.
The radiobiocomplexes labeled with technetium-99m (Tc-99m) have been widely used in nuclear medicine in single photon emission computed tomography and in basic research. The aim of this study was to assess the influence of a Nectandra membranácea extract on the bioavailability of the sodium pertechnetate (Na99mTc0(4)) radiobiocomplex in rat organs. The animals were treated with a N. membranácea extract (30 mg/ ml), for 6 days. Na99mTc0(4) was injected, the organs were isolated and weighed, and the radioactivity was determined in each organ (%ATI/organ). The %ATI/organ was divided by the mass of each organ to calculate the %ATI/g. A significant increase of the %ATI/organ of Na99mTc0(4) was observed in muscle and thyroid as well as in the %ATI/g in the...
Tipo: Journal article Palavras-chave: Nectandra membranácea; Bioavailability; Sodium pertechnetate; Radiobiocomplex.
Ano: 2007 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602007000200004
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