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KOLLING,JENIFER; KOLLING,JANAÍNA; FRANCESCHI,ITIANE D. DE; NISHIHIRA,VIVIAN S.K.; BALDISSERA,MATHEUS D.; PINTO,CLÁUDIA G.; MEZZOMO,NATHANA J.; CARMO,GUILHERME M. DO; FEKSA,LUCIANE R.; FERNANDES,LIANA S.; ORENGO,GILBERTO; VAUCHER,RODRIGO A.; GIONGO,JANICE L.; WYSE,ANGELA T.S.; WANNMACHER,CLOVIS M.D.; RECH,VIRGINIA C.. |
Abstract: Type 1 diabetes (T1D) is the result of the selective destruction of the pancreatic β-cells by T cells of the immune system. Although spleen is a secondary lymphoid organ, it is also involved in the T1D pathogenesis. However, the alterations in a variety of cellular processes of this disease need to be further understood. We aimed to analyze the benefits of resveratrol, and its complexed form on diabetic complications in the spleen of rats. To this end, we investigated important enzymes of phosphoryl transfer network, and Na+, K+-ATPase activity. Wistar rats were divided into non-diabetic groups: Control, Ethanol, Resveratrol, Hydroxypropyl-β-cyclodextrin, Resveratrol-hydroxypropyl-β-cyclodextrin, and diabetic groups with the same treatments.... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Energy metabolism; Hydroxypropyl-β-cyclodextrin; Hyperglycemia; Nanotecnology. |
Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000500701 |
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