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The Role of Apollon Gene Silencing on Viablity and Radiosensitivity of Cervical Cancer Hela Cells BABT
Milani,Saeideh; Bandehpour,Mojgan; Sharifi,Zohreh; Kazemi,Bahram.
Cervical cancer is the second common cause of cancer deaths in women worldwide. Radioresistancy of cancer is a principal cause of treatment impairing. Inhibitor of apoptosis proteins (IAPs) widely block apoptosis against apoptotic stimuli, including current chemo- and radiation therapies. Apollon, a membrane of IAP, can support cells against apoptosis and is over expressed in some treatment-resistant cancer cells. The aim of this study was to evaluate the effects of apollon knockdown on induction of apoptosis and also its potential for enhancement of radiosensitvity on hela cells. plasmid encoding shRNA which has been confirmed its effect against apollon, transfected into hela cells. Consequent effects on the level of P53 , Bax and BAK analyzed by real...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Apollon; Apoptosis; Radiosensitivity; Cervical cancer.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132016000100320
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Diagnosis of Helicobacter pylori infection by invasive and noninvasive tests BJM
Pourakbari,Babak; Ghazi,Mona; Mahmoudi,Shima; Mamishi,Setareh; Azhdarkosh,Hossein; Najafi,Mehri; Kazemi,Bahram; Salavati,Ali; Mirsalehian,Akbar.
Although several invasive and noninvasive tests have been developed for the diagnosis of Helicobacter pylori infection, all of the tests have their limitations. We conducted a study to investigate and compare the suitability of rapid urease test (RUT), serology, histopathology and stool antigen tests with polymerase chain reaction (PCR) for detection of H. pylori, and correlate the diagnostic methods with PCR. Eighty nine patients (61 adults, 28 children) referred to the Firoozgar Hospital and Children Medical Center Hospital for diagnostic upper gastrointestinal endoscopy entered to the study and noninvasive tests such as immunoassay for serological antibodies against H. pylori and detection of its antigen in feces were measured. The biopsies were...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Helicobacter pylori; Diagnosis; Invasive and noninvasive tests.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822013000300020
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