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	Provedor de dados BJMBR (2) Autor Koh,I.H.J. (2) Brunialti,M.K.C. (1) Gomes,T.A.T. (1) Junqueira,V.B.C. (1) Liberatore,A.M.A. (1) Menchaca-Diaz,J.L. (1) Moreira,F.C. (1) Oliveira-Junior,I.S. (1) Salomão,R. (1) Mais... Palavra-chave Acute lung injury (1) Atypical EPEC (1) Bacterial translocation (1) Enteropathogenic Escherichia coli (EPEC) (1) Inflammatory mediators (1) Microcirculation (1) Neutrophils (1) Pentoxifylline (1) Sepsis (1) Tissue perfusion (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2011 (1) 2006 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Effect of pentoxifylline on lung inflammation and gas exchange in a sepsis-induced acute lung injury model BJMBR Oliveira-Junior,I.S.; Brunialti,M.K.C.; Koh,I.H.J.; Junqueira,V.B.C.; Salomão,R.. Experimental models of sepsis-induced pulmonary alterations are important for the study of pathogenesis and for potential intervention therapies. The objective of the present study was to characterize lung dysfunction (low PaO2 and high PaCO2, and increased cellular infiltration, protein extravasation, and malondialdehyde (MDA) production assessed in bronchoalveolar lavage) in a sepsis model consisting of intraperitoneal (ip) injection of Escherichia coli and the protective effects of pentoxifylline (PTX). Male Wistar rats (weighing between 270 and 350 g) were injected ip with 10(7) or 10(9) CFU/100 g body weight or saline and samples were collected 2, 6, 12, and 24 h later (N = 5 each group). PaO2, PaCO2 and pH were measured in blood, and cellular influx,... Tipo: Info:eu-repo/semantics/article Palavras-chave: Acute lung injury; Sepsis; Inflammatory mediators; Pentoxifylline; Neutrophils. Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006001100009 Typical and atypical enteropathogenic Escherichia coli bacterial translocation associated with tissue hypoperfusion in rats BJMBR Liberatore,A.M.A.; Moreira,F.C.; Gomes,T.A.T.; Menchaca-Diaz,J.L.; Koh,I.H.J.. Although enteropathogenic Escherichia coli (EPEC) are well-recognized diarrheal agents, their ability to translocate and cause extraintestinal alterations is not known. We investigated whether a typical EPEC (tEPEC) and an atypical EPEC (aEPEC) strain translocate and cause microcirculation injury under conditions of intestinal bacterial overgrowth. Bacterial translocation (BT) was induced in female Wistar-EPM rats (200-250 g) by oroduodenal catheterization and inoculation of 10 mL 10(10) colony forming unit (CFU)/mL, with the bacteria being confined between the duodenum and ileum with ligatures. After 2 h, mesenteric lymph nodes (MLN), liver and spleen were cultured for translocated bacteria and BT-related microcirculation changes were monitored in... Tipo: Info:eu-repo/semantics/article Palavras-chave: Enteropathogenic Escherichia coli (EPEC); Atypical EPEC; Bacterial translocation; Microcirculation; Tissue perfusion. Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011001000007 Registros recuperados: 2 Primeira ... 1 ... Última

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