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	Provedor de dados BJPS (2) Autor Kohli,Kanchan (2) Beg,Sarwar (1) Hasnain,MS (1) Nayak,Amit Kumar (1) Pai,Raveendra (1) Shrivastava,Birendra (1) Swain,Suryakanta (1) Mais... Palavra-chave Chronotherapeutics (1) Extrusion/spheronization technique (1) In vitro dissolution (1) Minimum inhibitory concentration (1) Pellets/compression (1) Pellets/evaluation (1) Pellets/extended release (1) Pellets/obtention (1) Time-dependent release (1) Zone of inhibition (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2012 (2) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Compression and evaluation of extended release matrix pellets prepared by the extrusion/spheronization process into disintegrating tablets BJPS Pai,Raveendra; Kohli,Kanchan; Shrivastava,Birendra. In this study, a novel approach for compression of matrix pellets into disintegrating tablets has been studied in an attempt to overcome the issues pertaining to rupture of polymer coat during compression of reservoir-type pellets. Extended release matrix pellets were prepared by the extrusion/spheronization technique using commercially available aqueous dispersions of ethyl cellulose, acrylic polymers and sodium alginate at 10%, 20% and 30%w/w levels. Sertraline hydrochloride was used as the model drug and an in vitro release profile of 12 h was targeted. Tablets containing matrix pellets were prepared by the direct compression process. Acceptance Value, a pharmacopeial test, was applied to study the uniformity of drug distribution. Effect of compression... Tipo: Info:eu-repo/semantics/article Palavras-chave: Pellets/extended release; Pellets/evaluation; Pellets/obtention; Pellets/compression; Extrusion/spheronization technique. Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502012000100014 Antimicrobial activity assessment of time-dependent release bilayer tablets of amoxicillin trihydrate BJPS Beg,Sarwar; Nayak,Amit Kumar; Kohli,Kanchan; Swain,Suryakanta; Hasnain,MS. The aim of present study was the assessment of antimicrobial activity of prepared time-dependent release bilayer tablets of amoxicillin trihydrate and in vitro evaluation of drug release by antimicrobial assay using agar plate diffusion method. The bilayer tablets comprised of a delayed and sustained release layer. Direct compression method was used for the preparation of bilayer tablets containing Eudragit-L100 D55 as delayed release polymer, and HPMCK4M and HPMCK15 as sustained release polymers. The prepared bilayer tablets containing amoxicillin trihydrate were evaluated for hardness, thickness, friability, weight variation and drug content. Further, in vitro drug release was assessed by antimicrobial assay using S. aureus and E. coli as test... Tipo: Info:eu-repo/semantics/article Palavras-chave: Chronotherapeutics; Time-dependent release; In vitro dissolution; Minimum inhibitory concentration; Zone of inhibition. Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502012000200010 Registros recuperados: 2 Primeira ... 1 ... Última

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