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| Kondo,William; Carraro,Elaine Aparecida; Prandel,Elaine; Dias,Josiane Mourão; Perini,Juliane; Macedo,Rodolfo Lara de; Cornelsen,Taynah Cristina; Sbalquiero,Renato; Sasaki,Maria das Graças. |
| Nevirapine-based therapy is associated with increased frequency of adverse events among HIV-infected pregnant women. The aim of this article was to evaluate the incidence of adverse effects in HIV-infected women who started nevirapine during pregnancy. A retrospective study was performed in our center between January 2003 and December 2006 analyzing all women prescribed nevirapine during pregnancy. Women presenting any risk factor for hepatotoxicity were excluded from the analysis. Patients were divided into two groups according to the presence or absence of adverse effects, and a correlation to CD4 counts was performed. Liver function abnormality was graded according to the Division of AIDS toxicity guidelines. A total of 170 women initiated nevirapine... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Hepatotoxicity; HIV-1; Nevirapine; Pregnancy; Toxicity. |
| Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702007000600004 |
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| Rocha,Jaime Luís Lopes; Kondo,William; Baptista,Maria Inêz Domingues Kuchiki; Cunha,Clovis Arns da; Martins,Luzilma Terezinha Flenik. |
| Vancomycin has been used with increased frequency during the past 15 years and the most common toxicity with this drug is the "red man syndrome". Other adverse effects include neutropenia, fever, phlebitis, nephrotoxicity, ototoxicity, thrombocytopenia, interstitial nephritis, lacrimation, linear IgA bullous dermatosis, necrotizing cutaneous vasculitis and toxic epidermal necrolysis. Only two cases of vancomycin-induced Stevens-Johnson syndrome and one case of pancytopenia have been reported in the medical literature. The treatment for both situations is based on cessation of the vancomycin therapy; in cases of Stevens-Johnson syndrome, antihistamine and/or steroid agents can be used. This article reports a case of pancytopenia and a case of erythema major... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Vancomycin; Stevens-Johnson; Pancytopenia; Reactions; Thrombocytopenia. |
| Ano: 2002 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702002000400007 |
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