|
|
|
|
|
| Cerda,Oscar A; Núñez-Villena,Felipe; Soto,Sarita E; Ugalde,José Manuel; López-Solís,Remigio; Toledo,Héctor. |
| About half of the human population is infected with Helicobacter pylori, a bacterium causing gastritis, peptic ulcer and progression to gastric cancer. Chemotaxis and flagellar motility are required for colonization and persistence of H. pylori in the gastric mucus layer. It is not completely clear which chemical gradients are used by H. pylori to maintain its position. TlpA, a chemotaxis receptor for arginine/ bicarbonate, has been identified. This study aimed to find out whether tlpA gene expression is required for the chemotactic response to arginine/bicarbonate. Wild-type motile H. pylori ATCC 700392 and H. pylori ATCC 43504, a strain having an interrupted tlpA gene, were used. Also, a tlpA-knockout mutant of H. pylori 700392 (H. pylori 700-tlpA::cat)... |
| Tipo: Journal article |
Palavras-chave: TlpA; Chemotaxis; Helicobacter pylori; Arginine; Bicarbonate. |
| Ano: 2011 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602011000300009 |
| |
|
|
| Traipe-Castro,Leonidas; Salinas-Toro,Daniela; López,Daniela; Zanolli,Mario; Srur,Miguel; Valenzuela,Felipe; Cáceres,Aníbal; Toledo-Araya,Héctor; López-Solís,Remigio. |
| BACKGROUND: Fern-like crystalloids form when a microvolume of tear is allowed to dry out at ambient conditions on a glass surface. Presence of crystalloids in tear "microdesiccates" is used to evaluate patients with Dry-Eye disease. This study aims to examine morphologically the desiccation process of normal tear fluid and to identify changes associated with accelerated tear evaporation. Tear microdesiccates from healthy (Non-Dry Eye) and Dry Eye subjects were produced at ambient conditions. Microdesiccate formation was monitored continuously by dark-field video microscopy. Additionally, accelerated desiccation of tear samples from healthy subjects was conducted under controlled experimental conditions. Particular morphological domains of tear... |
| Tipo: Journal article |
Palavras-chave: Tear; Tear ferning test; Dry eye; Dark-field microscopy. |
| Ano: 2014 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602014000100025 |
| |
|
|
|
