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Genotoxic Maillard byproducts in current phytopharmaceutical preparations of Echinodorus grandiflorus Anais da ABC (AABC)
LIMA-DELLAMORA,ELISANGELA C.; WALDHELM,KASSIA C.V.; ALVES,ADRIANA M.; LAGE,CLAUDIA A.S.; LEITÃO,ALVARO A.C.; KUSTER,RICARDO M..
Extracts of Echinodorus grandiflorus obtained from dried leaves by three different techniques were evaluated by bacterial lysogenic induction assay (Inductest) in relation to their genotoxic properties. Before being added to test cultures, extracts were sterilized either by steam sterilization or ultraviolet light. Only the extracts prepared by infusion and steam sterilized have shown genotoxic activity. The phytochemical analysis revealed the presence of the flavonoids isovitexin, isoorientin, swertisin and swertiajaponin, isolated from a genotoxic fraction. They were assayed separately and tested negative in the Inductest protocol. The development of browning color and sweet smell in extracts submitted to heat, prompted further chemical analysis in...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Echinodorus grandiflorus; Genotoxicity; Maillard's Reaction; Flavonoids.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652014000301385
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