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Gastroprotective effect of Lagenocarpus rigidus (Kunth) Ness (tirica-do-nativo) leaf extract against indomethacin-induced gastric injury Plantas Medicinales
Lacerda Lopes Martins,Monica; Endringer Pinto,Fernanda; Uggere de Andrade,Tadeu; Lenz,Dominik; Costa Pereira,Thiago de Melo; Coutinho Endringer,Denise.
Introduction: species of the family Cyperaceae are commonly used by the population to treat gastric disorders.However, there are a few ethnopharmacological studies about this family Lagenocarpus rigidus (Kunth) Ness, Cyperaceae, is one of the most widespread swamp species. Objective: evaluate the gastric activity of L. rigidus and its chemical characterization. Methods: ethanolic extract of L. rigidus (ELR) leaves prepared by percolation was subjected to total polyphenol and flavonoid quantification, as well as HPLC quantification of some flavonoids. Angiotensin converting enzyme (ACE) inhibition was determined by colorimetric assays.The gastric effects of ELR were tested in male Wistar rats (n = 6 each group) treated with different doses (600, 60 and 6...
Tipo: Journal article Palavras-chave: Cyperaceae anti-ulcerogenic flavonoids; L rigidus phenolic compound.
Ano: 2014 URL: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1028-47962014000200001
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