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| Anne, Marie-laure; Keirsse, Julie; Nazabal, Virginie; Hyodo, Koji; Inoue, Satoru; Boussard-pledel, Catherine; Lhermite, Herve; Charrier, Joel; Yanakata, Kiyoyuki; Loreal, Olivier; Le Person, Jenny; Colas, Florent; Compere, Chantal; Bureau, Bruno. |
| Due to the remarkable properties of chalcogenide (Chg) glasses, Chg optical waveguides should play a significant role in the development of optical biosensors. This paper describes the fabrication and properties of chalcogenide fibres and planar waveguides. Using optical fibre transparent in the mid-infrared spectral range we have developed a biosensor that can collect information on whole metabolism alterations, rapidly and in situ. Thanks to this sensor it is possible to collect infrared spectra by remote spectroscopy, by simple contact with the sample. In this way, we tried to determine spectral modifications due, on the one hand, to cerebral metabolism alterations caused by a transient focal ischemia in the rat brain and, in the other hand, starvation... |
| Tipo: Text |
Palavras-chave: Planar waveguide; Fibre; Optical sensor; Chalcogenide. |
| Ano: 2009 |
URL: http://archimer.ifremer.fr/doc/2009/publication-6851.pdf |
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| Le Person, Jenny; Colas, Florent; Compere, Chantal; Lehaitre, Michel; Anne, M; Boussard Pledel, C; Bureau, B; Adam, J; Deputier, S; Guilloux Viry, M. |
| The surface plasmon resonance phenomenon has been studied in a chalcogenide glass-based optical system. IR transmission properties of these materials combined to their high refractive indices lead to advantageous properties for sensing. In this study, numerical simulations have been carried out to investigate the potentialities of sulfide glass from the GeGaSbS system as a coupling prism material. Then, an angular modulation SPR biosensor has been set up in the Kretschmann-Raether arrangement. Experimental data are consistent with numerical calculation and the detection limit of the sensor is 3 x 10(-5) RIU. These preliminary results are promising. Further investigations have to be carried out to confirm the great potentialities of those materials for... |
| Tipo: Text |
Palavras-chave: Infrared; Biosensor; Surface plasmon resonance; Chalcogenide glass. |
| Ano: 2008 |
URL: http://archimer.ifremer.fr/doc/2008/publication-3955.pdf |
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| Le Person, Jenny; Compere, Chantal; Lehaitre, Michel; Anne, Marie-laure; Boussard-pledel, Catherine; Bureau, Bruno; Adam, Jean-luc; Guilloux-viry, M; Burel, L. |
| Toxic algal blooms are a public health issue and constitute a menace for coastal areas. The potentiality of a chalcogenide optical fibre biosensor, operating in the mid-infrared (MIR) spectral domain, is studied. In order to monitor blooms of toxic algae, more specifically Alexandrium minutum specie, two ways are explored: immuno-biosensing and DNA identification. |
| Tipo: Text |
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| Ano: 2005 |
URL: http://archimer.ifremer.fr/doc/00089/19993/17656.pdf |
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