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| Cachot, Jerome; Bultelle, Florence; Drouot, Laurent; Galgani, Francois; Frebourg, Thierry; Leboulenger, François; Danger, Jean-michel. |
| Screening of a flounder ovary cDNA library with a rainbow trout p53 probe led to the isolation of a p53-unrelated cDNA encoding an unknown 161 amino acid protein. In view of its apparent molecular weight and yet unknown function, the deduced protein was named Xp18. Corresponding orthologous cDNAs or expressed sequence tags have been identified in several species including human, rodents, bovine, chicken and zebrafish and a related cDNA has also been isolated in the fruit fly. Deduced amino acid sequences appeared to be extremely well conserved throughout vertebrate evolution. Structure predictions suggested that Xp 18 may correspond to an integral protein comprising four transmembrane domains. The charged C-termini of all known vertebrate Xp18-like... |
| Tipo: Text |
Palavras-chave: X chromosome; Brain; Ovary; Human; Teleostean; Platichthys flesus. |
| Ano: 2003 |
URL: http://archimer.ifremer.fr/doc/2003/publication-756.pdf |
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| Minier, Christophe; Abarnou, Alain; Jaouen Madoulet, Agnes; Le Guellec, Anne-marie; Tutundjian, Renaud; Bocquene, Gilles; Leboulenger, François. |
| Zebra mussel (Dreissena polymorpha) is an invasive species that has proliferated in European and North American rivers and lakes during the last century. In this study, D. polymorpha has been used to provide information on contamination levels and biological effects in the Seine Estuary (France). The bivalves accumulated polychlorinated biphenyls (PCBs) and polycyclic aromatic hydrocarbons (PAHs) to a high degree with values reaching 800 ng/g dry weight for PCBs (sum of 20 congeners), and 1,000 ng/g dry weight of PAHs (sum of 14 compounds) in the whole body. These values are among the highest reported of PCBs and, to a lesser extent, of PAHs in other contaminated areas in the world. Toxic equivalent quantities of PCBs and PAHs detected in zebra mussels... |
| Tipo: Text |
Palavras-chave: Biomarkers; Multixenobiotic resistance; Polycyclic aromatic hydrocarbons; Polychlorinated biphenyls; Dreissena polymorpha. |
| Ano: 2006 |
URL: http://archimer.ifremer.fr/doc/2006/publication-2130.pdf |
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