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	Provedor de dados Nature Precedings (2) Autor Hoi Shan Kwan (2) Lei LI (2) Man Kit Cheung (2) Wenyan Nong (2) Palavra-chave Bioinformatics (2) Genetics & Genomics (2) Microbiology (2) Evolutionary Biology (1) Tipo do documento Manuscript (2) Ano 2011 (2) País United Kingdom (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última 2011 German Escherichia coli outbreak: Alignment-free whole-genome phylogeny by feature frequency profiles Nature Precedings Man Kit Cheung; Lei LI; Wenyan Nong; Hoi Shan Kwan. Accuracy of SNP-based whole-genome phylogeny reconstruction relies heavily on quality of sequence alignment which is particularly hindered by poorly assembled genomes. Alignment-free methods might provide additional insights. Here, we constructed a whole-genome phylogeny of 9 E.coli isolates from the 2011 German outbreak against existing E. coli genomes using the alignment-free feature frequency profile method. In addition, we looked for gene elements that distinguish the outbreak group from the other E. coli strains and possibly accounted for the emergence of the outbreak isolates using the distinguishing feature analysis. Tipo: Manuscript Palavras-chave: Genetics & Genomics; Microbiology; Bioinformatics; Evolutionary Biology. Ano: 2011 URL: http://precedings.nature.com/documents/6109/version/1 2011 German Escherichia coli outbreak: Prophage analysis of close-assembled TY2482 against 55989 using PHAST Nature Precedings Man Kit Cheung; Lei LI; Wenyan Nong; Hoi Shan Kwan. Using the Hiseq data of the German E. coli outbreak isolate TY2482, preliminary prophage analyses have been performed by some researchers previously. With the closed assembly of the same isolate being available, another round of analysis might help in resolving questions that remain unclear due to the incompleteness of the dataset. Tipo: Manuscript Palavras-chave: Genetics & Genomics; Microbiology; Bioinformatics. Ano: 2011 URL: http://precedings.nature.com/documents/6110/version/1 Registros recuperados: 2 Primeira ... 1 ... Última

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