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Lamellar keratoplasty in rabbits using an allogeneic free omental graft and omentum-derived mesenchymal cells associated with the canine amniotic membrane Ciência Rural
Barros,Séfora Vieira da Silva Gouvêa de; Aldrovani,Marcela; Lacerda,Luciana Cenço Correa de; Horr,Mônica; Marinho,Fábio Andrade; Lima,Tiago Barbalho; Silveira,Camila Pinho Balthazar da; Brito,Fábio Luiz da Cunha; Bassaneze,Vinícius; Flecher,Mayra Cunha; Beltrame,Renato Travassos; Nakamuta,Juliana Sanajotti; Krieger,José Eduardo; Laus,José Luiz; Oliveira,Krishna Duro de.
ABSTRACT: The objective of this research was to evaluate the clinical and microscopic effects in rabbits of lamellar keratoplasty using allogeneic omentum associated with canine amniotic membrane (AM). Rabbits were divided into two groups: one received the allogeneic free omental graft covered with the AM (OM-graft group), while the other received the AM graft containing omental mesenchymal cells (OM-cell group). Clinical signs were evaluated on different postoperative days. After the clinical assessments, the rabbits were euthanized and their corneas were obtained for histopathology and immunohistochemistry (Ki-67, marker for proliferation). Both groups showed chemosis, blepharospasm, eye discharge, hyperemia, and corneal opacity/edema. Neovascularization...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Amniotic membrane; Cornea; Omentum; Progenitor cells; Wound healing..
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782016001001838
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Effect of an intravitreal dexamethasone device on ocular inflammation after phacoemulsification in dogs Ciência Rural
Lima,Tiago Barbalho; Padua,Ivan Martinez; Kobashigawa,Karina Kamachi; Aldrovani,Marcela; Chacaltana,Flor Diana Yocoay Claros; Santo,Paloma do Espírito; Vieira,Lorena Carla; Barros Sobrinho,Alexandre Augusto Franchi; Cunha Junior,Armando Silva; Laus,José Luiz.
ABSTRACT: This study examined the efficacy of an intravitreal dexamethasone-loaded device for the control of postoperative ocular inflammation in dogs following phacoemulsification. Twenty dogs with bilateral mature senile cataracts were prepared for surgery using routine protocols. A biodegradable poly (lactic-co-glycolic acid) copolymer device was inserted through the pars plana into the vitreous chamber immediately before phacoemulsification (device group [DG], n=20). Following surgery, a conventional group (CG) received local and systemic steroids, mydriatics, and antibiotic therapy. The same treatment protocol was adopted in DG, except for steroids. All eyes were examined before surgery and at various times after phacoemulsification. Ultrasonography...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Dog; Cataract surgery; Inflammation; PLGA; Dexamethasone.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782016001202216
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Ophthalmic parameters in adult Shih Tzu dogs Ciência Rural
Kobashigawa,Karina Kamachi; Lima,Tiago Barbalho; Padua,Ivan Ricardo Martinez; Barros Sobrinho,Alexandre Augusto Franchi de; Marinho,Fabio de Andrade; Ortêncio,Kethye Priscila; Laus,José Luiz.
Ocular surface diseases are often diagnosed in brachycephalic dogs. The ophthalmic parameters of the Shih Tzu dogs are evaluated in this study since this breed is among the most commonly affected by these diseases. In this study, ophthalmic parameters of this breed were partly studied under physical restraint. Schirmer tear test, breakup time test, aesthesiometry, biomicroscopy, non-contact specular microscopy, laser flaremetry, applanation tonometry, ultrasonography and ophthalmoscopy were carried in 48 eyes of 24 male and female dogs, aged from two to four years, weighing between 5 and 10kg. All dogs were from a breeding kennel. Descriptive statistics were applied to the data. Mean and standard error for Schirmer tear test was 26.145±0.803mm min-1;...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Dog; Shih Tzu; Ophthalmic parameters..
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782015000701280
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