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| Gong,Zheng; Luo,Qi-Zhi; Lin,Lin; Su,Yu-Ping; Peng,Hai-Bo; Du,Kun; Yu,Ping; Wang,Shi-Ping. |
| Major histocompatibility complex class I chain-related A (MICA) is a highly polymorphic gene located within the MHC class I region of the human genome. Expressed as a cell surface glycoprotein, MICA modulates immune surveillance by binding to its cognate receptor on natural killer cells, NKG2D, and its genetic polymorphisms have been recently associated with susceptibility to some infectious diseases. We determined whether MICA polymorphisms were associated with the high rate of Schistosoma parasitic worm infection or severity of disease outcome in the Dongting Lake region of Hunan Province, China. Polymerase chain reaction-sequence specific priming (PCR-SSP) and sequencing-based typing (SBT) were applied for high-resolution allele typing of... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Schistosoma japonicum; MICA; NKG2D; Gene polymorphism; Liver fibrosis. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000300007 |
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| Yang,Guodong; Li,Peng; Meng,Lifen; Xv,Keyi; Dong,Faming; Qiu,Yan; He,Lei; Lin,Lin. |
| Abstract To know more about the potential roles of endophytic fungi in the formation mechanism of Daodi medicinal material, diversity and communities of culturable endophytic fungi in three types of tree peonies were investigated. Endophytic fungi of three types of tree peonies were isolated and identified. The diversity was analyzed. Bayesian trees constructed by MrBayes 3.2.6 after phylogenetic analysis of the ITS sequences. The endophytic fungi potential for synthesis of natural products was assessed by means of detecting NRPS and PKS gene sequences. In total, 364 endophytic fungi isolates representing 26 genera were recovered from Paeonia ostii ‘Feng Dan’, Paeonia ostii ‘Luoyang Feng Dan’, and Paeonia suffruticosa ‘Luoyang Hong’. More culturable... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Endophytic fungi; PKS; NRPS; Cortex Moutan; Daodi medicinal material. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822018000500047 |
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