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| Neves,Francelli Cordeiro; Clemente,Wanessa T.; Lincopan,Nilton; Paião,Isabela D.; Neves,Patrícia R.; Romanelli,Roberta M.; Lima,Stella S.S.; Paiva,Luciene F.; Mourão,Paulo Henrique O.; Nobre-Junior,Vandack A.. |
| ABSTRACT Background: Carbapenem-resistant Acinetobacter baumannii (CRAb) is an important cause of nosocomial infections especially in intensive care units. This study aimed to assess clinical aspects and the genetic background of CRAb among ICU patients at a Brazilian teaching hospital. Methods: 56 critically ill patients colonized or infected by CRAb, during ICU stay, were prospectively assessed. Based on imipenem MIC ≥ 4 µg/mL, 28 CRAB strains were screened for the presence of genes encoding metallo-β-lactamases and OXA-type β-lactamases. The blaOXA-type genes were characterized by PCR using primers targeting ISAba-1 or -3. Genetic diversity of blaOXA-positive strains was determined by ERIC-PCR analysis. Results: Patient's mean age (±SD) was 61... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Acinetobacter baumannii; Carbapenem resistance; BlaOXA-23; BlaOXA-143. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000600556 |
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| Ribeiro,Vinicius B.; Lincopan,Nilton; Landgraf,Mariza; Franco,Bernadete D.G.M.; Destro,Maria T.. |
| In recent years, an increase in the occurrence of antimicrobial resistance among Salmonella enterica has been observed in several countries, which is worrisome because S. enterica is one of the most common causes of human gastroenteritis worldwide. The aim of this study was to characterize class 1 integrons and antibiotic resistance genotypes in Salmonella enterica isolates recovered from foodstuff and related sources. Nineteen multidrug-resistant (MDR) Salmonella enterica isolates were recovered. Higher resistance rates to tetracycline (90%), streptomycin (80%), sulfamethoxazole-trimethoprim (80%), ampicillin (60%) and nalidixic acid (70%) were related to the presence of the tetA, aadA, sul1/sul2, blaTEM-1 genes, and a codon mutation at position 83 of the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Salmonella; Multidrug-resistant; Class 1 integrons; Foodstuff; Brazil. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822011000200033 |
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| Balsalobre,Livia Carminato; Dropa,Milena; de Oliveira,Danielle Escudeiro; Lincopan,Nilton; Mamizuka,Elsa Masae; Matté,Glavur Rogério; Matté,Maria Helena. |
| It is known that Aeromonas spp. possess different chromosomal β-lactamase genes. Presence and phenotypic expression of blaTEM, blaSHV, and blaCTX-M ESBL-encoding genes were investigated in environmental water isolates of Aeromonas hydrophila and Aeromonas jandaei. Presence of blaSHV and blaCTX-M genes was not observed, and blaTEM gene was verified in 91% of the isolates. Sequencing of 10 fragments showed the occurrence of blaTEM-116. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Aeromonas; Environmental isolates. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822010000300023 |
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