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| Favero-Filho,L.A.; Borges,A.A.; Grassl,C.; Lopes,A.C.; Sinigaglia-Coimbra,R.; Coimbra,C.G.. |
| Chronic neurodegenerative processes have been identified in the rat forebrain after prolonged survival following hyperthermia (HT) initiated a few hours after transient global ischemia. Since transient global ischemia and ischemic penumbra share pathophysiological similarities, this study addressed the effects of HT induced after recirculation of focal brain ischemia on infarct size during long survival times. Adult male Wistar rats underwent intra-luminal occlusion of the left middle cerebral artery for 60 min followed by HT (39.0-39.5°C) or normothermia. Control procedures included none and sham surgery with and without HT, and middle cerebral artery occlusion alone. Part I: 6-h HT induced at recirculation. Part II: 2-h HT induced at 2-, 6-, or 24-h... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Hyperthermia; Ischemic penumbra; Neurodegeneration; Rat focal ischemia. |
| Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008001100014 |
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| Pereira Filho,M.A.; Pereira,L.A.A.; Arbex,F.F.; Arbex,M.; Conceição,G.M.; Santos,U.P.; Lopes,A.C.; Saldiva,P.H.N.; Braga,A.L.F.; Cendon,S.. |
| Type 2 diabetes increases the risk of cardiovascular mortality and these patients, even without previous myocardial infarction, run the risk of fatal coronary heart disease similar to non-diabetic patients surviving myocardial infarction. There is evidence showing that particulate matter air pollution is associated with increases in cardiopulmonary morbidity and mortality. The present study was carried out to evaluate the effect of diabetes mellitus on the association of air pollution with cardiovascular emergency room visits in a tertiary referral hospital in the city of São Paulo. Using a time-series approach, and adopting generalized linear Poisson regression models, we assessed the effect of daily variations in PM10, CO, NO2, SO2, and O3 on the daily... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cardiovascular diseases; Diabetes; Air pollution; Emergency room visits; Time-series study. |
| Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008000600015 |
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