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Metabolic and behavioral effects of ractopamine at continuous low levels in rats under stress BABT
Lopes,Edna; Sousa,Raimundo Vicente de; Zangeronimo,Márcio Gilberto; Pereira,Andressa Naira de Jesus; Coelho,Mariana de Resende; Ferreira,Matheus Soares da Silva; Lima,Renato Ribeiro; Marcondes,Fernanda Klein; Napimoga,Marcelo Henrique; Pereira,Luciano José.
This study aimed at evaluating the effect of ractopamine (RAC) on metabolism, zootechnical performance, body composition, and behavior in Wistar rats submitted to acute and chronic restrain stress. The oral dose of 5 mg/kg of RAC was administered in periods of 0, 7, 14, 21, and 28 days. The elevated plus-maze test (EPMT) was used for behavioral assessment. Blood, carcass and viscera characteristics were evaluated. Insulin-dependent glucose transporters (GLUT-4) were semi-quantified by Western Blot in epididymal adipocytes. RAC periods associated with chronic stress increased the GLUT-4 protein expression in adipose tissue in a time-dependent manner (P=0.01), i.e., the longer the RAC addition period, the higher the GLUT-4 concentration in chronically...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Β-adrenergic agonist; Ractopamine; Zootechnical performance; Metabolism; Elevated Plus-Maze Tests.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132015000300406
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