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| Registros recuperados: 99 | |
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| Canaza-Cayo,Ali William; Lopes,Paulo Sávio; Silva,Marcos Vinicius Gualberto Barbosa da; Cobuci,Jaime Araújo; Torres,Robledo de Almeida; Martins,Marta Fonseca; Arbex,Wagner Antonio. |
| O objetivo neste estudo foi avaliar a estrutura genética da população de bovinos da raça Girolando no Brasil. Analisou-se o arquivo de pedigree de 26.969 animais, composto de 3.031 machos e 23.938 fêmeas. O nível de conteúdo de informação do pedigree na geração atual foi 61%, mostrando ser de qualidade moderada. O coeficiente de endogamia médio e o coeficiente de relação médio da população Girolando foram 0,11 e 0,13%, respectivamente. O tamanho efetivo da população, considerando a geração completa traçada, foi 188, acima do nível crítico. Do total de 9.457 ancestrais que contribuíram para a população de referência, 457 explicaram 50% da variabilidade genética da população. O número efetivo de fundadores foi 551 e o de ancestrais 393. O intervalo médio de... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Coeficiente de endogamia; Girolando; Tamanho efetivo populacional. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782014001102072 |
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| Macedo,Leandro Roberto de; Silva,Fabyano Fonseca e; Cirillo,Marcelo Ângelo; Nascimento,Moysés; Paixão,Débora Martins; Guimarães,Simone Eliza Facioni; Lopes,Paulo Sávio; Santos,Jussara Aparecida dos; Azevedo,Camila Ferreira. |
| Para avaliar a influência do gene halotano sobre a curva de crescimento de suínos, bem como sua interação com o sexo do animal, foi proposta uma modelagem hierárquica Bayesiana. Nesta abordagem, os parâmetros dos modelos não-lineares de crescimento (Logístico, Gompertz e von Bertalanffy) foram estimados conjuntamente com os efeitos de sexo e genótipos do gene halotano. Foram utilizados 344 animais F2(Comercial x Piau) pesados ao nascer, aos 21, 42, 63, 77, 105 e 150 dias. O modelo Logístico foi aquele que apresentou melhor qualidade de ajuste por apresentar menor DIC (Deviance Information Criterion) que os demais. As amostras das distribuições marginais a posteriori para as diferenças entre as estimativas dos parâmetros do modelo Logístico indicaram que o... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Melhoramento; Modelos não-lineares; Síndrome do estresse suíno. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782014001001853 |
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| Azevedo,Camila Ferreira; Silva,Fabyano Fonseca e; Rezende,Marcos Deon Vilela de; Peternelli,Luiz Alexandre; Guimarães,Simone Eliza Facione; Lopes,Paulo Sávio. |
| A principal contribuição da genética molecular é a utilização direta das informações de DNA no processo de identificação de indivíduos geneticamente superiores. Sob esse enfoque, idealizou-se a seleção genômica ampla (Genome Wide Selection - GWS), a qual consiste na análise de marcadores SNPs (Single Nucleotide Polymorphisms) amplamente distribuídos no genoma. Devido a esse grande número de SNPs, geralmente maior que o número de indivíduos genotipados, e à alta colinearidade entre eles, métodos de redução de dimensionalidade são requeridos. Dentre estes, destaca-se o método de regressão via Quadrados Mínimos Parciais (Partial Least Squares - PLS), que além de solucionar tais problemas, permite uma abordagem multivariada, considerando múltiplos fenótipos.... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Seleção genômica; Redução de dimensionalidade; Análise multivariada. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782013000900017 |
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| Abreu,Urbano Gomes Pinto de; Santos,Sandra Aparecida; Lopes,Paulo Sávio; Torres,Robledo de Almeida; Santos,Heleno do Nascimento. |
| A estrutura etária do rebanho e a estratégia de descarte de matrizes são pontos importantes na avaliação da eficiência do sistema de produção de gado de corte. Neste trabalho foi monitorado o rebanho de cria, cujas matrizes eram mantidas ou descartadas com base em critério técnico, conforme a avaliação do desempenho reprodutivo. Para tanto, foi utilizada a cadeia de Markov com o objetivo de simular a probabilidade de descarte por idade, ao longo da vida, e de calcular a expectativa de vida da matriz no rebanho. Após a introdução da estação de monta, a pressão de descarte foi maior, com aumento da probabilidade de descarte e da diminuição da probabilidade de permanência da matriz no rebanho nas idades mais avançadas. Com a introdução de tecnologias e... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Análise de sistema de produção; Descarte de matrizes; Introdução de tecnologias. |
| Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782008000900046 |
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| Silveira,Fernanda Gomes da; Duarte,Darlene Ana Souza; Chaves,Lucas Monteiro; Silva,Fabyano Fonseca e; Filho,Ivan Carvalho; Duarte,Marcio de Souza; Lopes,Paulo Sávio; Guimarães,Simone Eliza Facioni. |
| ABSTRACT: The main application of genomic selection (GS) is the early identification of genetically superior animals for traits difficult-to-measure or lately evaluated, such as meat pH (measured after slaughter). Because the number of markers in GS is generally larger than the number of genotyped animals and these markers are highly correlated owing to linkage disequilibrium, statistical methods based on dimensionality reduction have been proposed. Among them, the partial least squares (PLS) technique stands out, because of its simplicity and high predictive accuracy. However, choosing the optimal number of components remains a relevant issue for PLS applications. Thus, we applied PLS (and principal component and traditional multiple regression)... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: SNP; Genomic prediction; Meat quality. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782017000100652 |
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| Faria,Danielle Assis de; Guimarães,Simone Eliza Facioni; Lopes,Paulo Sávio; Pires,Aldrin Vieira; Paiva,Samuel Rezende; Sollero,Bruna Pena; Wenceslau,Amauri Arias. |
| The association between G316A growth hormone polymorphism and quantitative traits was investigated in an F2 population of pigs. Association analyses were performed using a statistical model that included genotype, sex, batch and sex by genotype interaction as fixed effects and sire as random effect. The polymorphism was associated with the number of right teats (p = 0.03), heart weight (p = 0.04), lung weight (p = 0.05), carcass length determined by the Brazilian carcass classification method (p = 0.04), picnic shoulder weight (p = 0.07), jowl weight (p = 0.01), pH 24 h after slaughtering (p = 0.03) and drip loss (p = 0.01). Interaction between genotype and sex was observed for six performance traits. The additive effect was significant (p < 0.10) for... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Candidate genes; Divergent cross; Molecular marker; Sex x genotype interaction; Swine. |
| Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572006000400010 |
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| Band,Guilherme de Oliveira; Guimarães,Simone Eliza Facioni; Lopes,Paulo Sávio; Peixoto,Jane de Oliveira; Faria,Danielle Assis; Pires,Aldrin Vieira; Figueiredo,Frederico de Castro; Nascimento,Carlos Souza do; Gomide,Lúcio Alberto de Miranda. |
| The PSS genotypes of 596 F2 pigs produced by initial mating of Brazilian native boars commercial sows and were characterized by PCR-RFLP and their carcass and performance traits were evaluated. Among the 596 animals analyzed, 493 (82.72%) were characterized as NN and 103 (17.28%) as Nn. With respect to carcass traits, Nn animals presented higher (p < 0.05) right half carcass weight, left half carcass weight, loin depth and loin eye area, and lower shoulder backfat thickness, backfat thickness between last and next to last but one lumbar vertebrae and backfat thickness after last rib at 6.5 cm from the midline compared to NN animals. Nn animals also showed (p < 0.05) higher values for most of the cut yields, indicating higher cutting yields for... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Carcass; Performance; PSS gene; PCR-RFLP; Pig. |
| Ano: 2005 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572005000100016 |
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| Torres Filho,Rodolpho de Almeida; Torres,Robledo de Almeida; Lopes,Paulo Sávio; Pereira,Carmen Silva; Euclydes,Ricardo Frederico; Araújo,Cláudio Vieira de; Silva,Martinho de Almeida e. |
| The selection and evaluation of breeds and purebred lines to be used as the parental stock is an important step for the success of any animal breeding program. In this study, the feed:gain ratio, backfat thickness corrected for 100 kg, age to 100 kg, average daily gain, and age of sow at first farrowing were used to evaluate the genetic trends for direct and maternal additive genetic values in Large White pigs. The total number of piglets born or born alive and the litter weight at birth were used as indicators of the genetic trends for the direct additive values. The genetic trends were calculated by regression of the average predicted genetic values per year for each trait versus the offspring's year of birth (for performance traits) or versus the dam... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Average daily gain; Backfat thickness; Birth litter weight. |
| Ano: 2005 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572005000100017 |
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| Cobuci,Jaime Araujo; Euclydes,Ricardo Frederico; Lopes,Paulo Sávio; Costa,Claudio Napolis; Torres,Robledo de Almeida; Pereira,Carmen Silva. |
| Test-day milk yield records of 11,023 first-parity Holstein cows were used to estimate genetic parameters for milk yield during different lactation periods. (Co)variance components were estimated using two random regression models, RRM1 and RRM2, and the restricted maximum likelihood method, compared by the likelihood ratio test. Additive genetic variances determined by RRM1 and additive genetic and permanent environmental variances estimated by RRM2 were described, using the Wilmink function. Residual variance was constant throughout lactation for the two models. The heritability estimates obtained by RRM1 (0.34 to 0.56) were higher than those obtained by RRM2 (0.15 to 0.31). Due to the high heritability estimates for milk yield throughout lactation and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Random regression models; REML method; Genetic parameters; Test-day milk yield; Holstein cows. |
| Ano: 2005 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572005000100013 |
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| Fonseca,Isabela; Silva,Priscila Vendramini; Lange,Carla Christine; Guimarães,Marta F.M.; Weller,Mayara Morena Del Cambre Amaral; Sousa,Katiene Régia Silva; Lopes,Paulo Sávio; Guimarães,José Domingos; Guimarães,Simone E.F.. |
| In order to characterize the expression of genes associated with immune response mechanisms to mastitis, we quantified the relative expression of the IL-2, IL-4, IL-6, IL-8, IL-10, IFN-γ and TNF-α genes in milk cells of healthy cows and cows with clinical mastitis. Total RNA was extracted from milk cells of six Black and White Holstein (BW) cows and six Gyr cows, including three animals with and three without mastitis per breed. Gene expression was analyzed by real-time PCR. IL-10 gene expression was higher in the group of BW and Gyr cows with mastitis compared to animals free of infection from both breeds (p < 0.05). It was also higher in BW Holstein animals with clinical mastitis (p < 0.001), but it was not significant when Gyr cows with and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cytokine; Gene expression; Immune response; Real-time PCR. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572009000400018 |
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| Carmo,Fausto Moreira da Silva; Guimarães,Simone Eliza Facioni; Lopes,Paulo Sávio; Pires,Aldrin Vieira; Guimarães,Marta Fonseca Martins; Silva,Marcos Vinícius Gualberto Barbosa da; Schierholt,Alex Sandro; Silva,Kleibe de Moraes e; Gomide,Lúcio Alberto de Miranda. |
| We studied the phenotypic effects of polymorphisms at the MYF5 gene in a divergent F2 swine population and found that one polymorphism was due to an insertion and another to a deletion. The genotypes of 359 F2 animals were obtained and the Normal/Normal (NN) and Normal/Insertion (NI) genotypes analyzed to determine associations with phenotypic data for performance, carcass and meat quality traits. Significant differences were observed (p < 0.05) between NN and NI animals for drip (NN = 3.14 ± 1.56; NI = 3.69 ± 2.78%), cooking (NN = 32.26 ± 2.41; NI = 33.21 ± 2.31%) and total loss (NN = 34.16 ± 2.63 and NI = 34.97 ± 2.08%). The Deletion marker was not statistically tested. The results indicate that the allelic variant Insertion is associated with a... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Myogenesis; DNA sequencing; Pig production; PCR. |
| Ano: 2005 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572005000300004 |
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| Silva,Kleibe de Moraes; Paixão,Débora Martins; Silva,Priscila Vendramini; Solero,Bruna Pena; Pereira,Mario Sérgio; Lopes,Paulo Sávio; Guimarães,Simone Eliza Facioni. |
| The objective was to map QTL on porcine chromosome 4 and to associate them with carcass and internal organ traits in an F2 population. The F1 population was produced by outbreed crossing, using two native Brazilian breed Piau boars and 18 commercial sows. A total of 617 F2 animals issued from 11 F1 boars and 54 F1 sows were typed for a total of five microsatellite markers. The data were analyzed by multiple regressions developed for the analysis of crosses between outbred lines, using the QTL Express software. Significant evidence for QTL was found for pig chromosome 4 regarding carcass and internal organ traits. All QTL were detected in the same region of the chromosome, designated FAT1. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Fatness; Pig production; Divergent crosses; Microsatellite markers; QTL mapping. |
| Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572008000300013 |
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| Band,Guilherme de Oliveira; Guimarães,Simone Eliza Facioni; Lopes,Paulo Sávio; Schierholt,Alex Sandro; Silva,Kleibe Moraes; Pires,Aldrin Vieira; Benevenuto Júnior,Augusto Aloísio; Gomide,Lúcio Alberto de Miranda. |
| The PSS genotypes of 596 F2 pigs produced by initial mating of Brazilian commercial sows and native boars were characterized by PCR-RFLP and the pork quality traits were evaluated. Among the 596 pigs studied, 493 (82.7%) were NN and 103 (17.3%) were Nn. There were no differences between NN and Nn pigs in the following pork qualities: pHu (5.71 ± 0.16 vs 5.70 ± 0.11), intramuscular fat (1.55 ± 0.64% vs 1.65 ± 0.67%), shear force (5552 ± 878 g/1.2 cm vs 5507 ± 826 g/1.2 cm), lightness (44.96 ± 2.05 vs 45.01 ± 1.92), redness (0.64 ± 0.60 vs 0.79 ± 0.55), yellowness (6.62 ± 0.56 vs 6.65 ± 0.48), hue (84.28 ± 5.53 vs 83.41 ± 4.85), or chroma (6.68 ± 0.52 vs 6.73 ± 0.52). However, pork from Nn pigs had a significantly (p < 0.05) lower pH45 (6.41 ± 0.27 vs... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Meat quality; PCR-RFLP; Pork; PSE; PSS; Pig. |
| Ano: 2005 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572005000100015 |
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| Mota,Rodrigo Reis; Lopes,Paulo Sávio; Marques,Luiz Fernando Aarão; Silva,Luciano Pinheiro da; Resende,Marcos Deon Vilela de; Torres,Robledo de Almeida. |
| The weight records from Simmental beef cattle were used in a genetic evaluation of growth with or without the inclusion of animals obtained by embryo transfer. A multi-trait model in which embryo transfer individuals were excluded (MTM1) contained 29,510 records from 10,659 animals, while another model without exclusion of these animals (MTM2) contained 62,895 weight records from 23,160 animals. The weight records were adjusted for ages of 100, 205, 365, 450, 550 and 730 days. The (co)variance components and genetic parameters were estimated by the restricted maximum likelihood method. The (co)variance components were similar in both models, except for maternal permanent environment variance. Direct heritabilities (h²d) in MTM1 were 0.04, 0.11, 0.20, 0.27,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Body weight; (co)variance components; Heritability. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572013000100007 |
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| Silva,Fabyano Fonseca e; Resende,Marcos Deon V. de; Rocha,Gilson Silvério; Duarte,Darlene Ana S.; Lopes,Paulo Sávio; Brustolini,Otávio J.B.; Thus,Sander; Viana,José Marcelo S.; Guimarães,Simone E.F.. |
| In the current post-genomic era, the genetic basis of pig growth can be understood by assessing SNP marker effects and genomic breeding values (GEBV) based on estimates of these growth curve parameters as phenotypes. Although various statistical methods, such as random regression (RR-BLUP) and Bayesian LASSO (BL), have been applied to genomic selection (GS), none of these has yet been used in a growth curve approach. In this work, we compared the accuracies of RR-BLUP and BL using empirical weight-age data from an outbred F2 (Brazilian Piau X commercial) population. The phenotypes were determined by parameter estimates using a nonlinear logistic regression model and the halothane gene was considered as a marker for evaluating the assumptions of the GS... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Bayesian LASSO; Nonlinear regression; SNP effects. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572013000400010 |
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| Araújo,Adriana Mello de; Guimarães,Simone Eliza Facioni; Machado,Thea Mírian Medeiros; Lopes,Paulo Sávio; Pereira,Carmen Silva; Silva,Francisco Luiz Ribeiro da; Rodrigues,Marcelo Teixeira; Columbiano,Virgínia de Souza; Fonseca,Cleusa Graça da. |
| Brazilian naturalized goat breeds are adapted to the semiarid conditions prevalent in the Northeast region of the country (which has the largest Brazilian goat heard) and represent an as yet uninvestigated source of genetic diversity. Currently, imported goat breeds are crossed with Brazilian naturalized goat breeds, endangering the genetic potential of the naturalized breeds. We used 11 microsatellite markers to determine the genetic diversity among imported (non-naturalized) dairy Alpine and Saanen goats and naturalized Brazilian Moxotó goats. We genotyped 292 goats from three herds (one private, one from the University of Minas Gerais and the Moxotó conservation herd from Embrapa Caprinos) and found that the general heterozygosity was 0.6952 for Alpine,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Conservation; DNA microsatellite; Genetic distance; Genetic diversity; Goats. |
| Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572006000100014 |
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| Rossi,Robson Marcelo; Martins,Elias Nunes; Lopes,Paulo Sávio; Silva,Fabyano Fonseca e. |
| O objetivo deste trabalho foi apresentar modelagens alternativas, uni e bivariadas, para avaliação da conversão alimentar (CA) de suínos da raça Piau, com uso de inferência bayesiana. Os efeitos de sexo e genótipo sobre a CA dos animais foram avaliados por meio de procedimentos de simulação de Monte Carlo via cadeias de Markov (MCMC) e de integração aproximada aninhada de Laplace (INLA). O modelo univariado foi avaliado com diferentes distribuições para o erro - normal (gaussiana), t de Student, gama, log-normal e skew-normal -, enquanto, para o modelo bivariado, considerou-se o erro normal. A distribuição skew-normal foi o modelo mais parcimonioso para inferir sobre a resposta direta (univariada) da CA aos efeitos de sexo e genótipo, os quais não foram... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Análise multivariada; Desempenho nutricional; INLA; MCMC; Síndrome do estresse suíno.. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-204X2014001000754 |
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| Registros recuperados: 99 | |
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