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| Golombieski,Ronaldo Medeiros; Graichen,Daniel Ângelo Sgranzerla; Rocha,João Batista Teixeira da; Valente,Vera Lúcia da Silva; Loreto,Élgion Lúcio da Silva. |
| Selenium is an important dietary micronutrient and an essential component of selenoproteins and the active sites of some enzymes, although at high concentrations it is toxic. We investigated diphenyl diselenide ((C6H5)2Se2 ) for its effects on the developmental stages of Drosophila melanogaster and found that in the larval and pupae stages the toxic threshold for this compound when added to the banana-agar medium on which the larva were fed was 350 µmol. In adult flies, fed on the same media, there were no observable toxic effects below 500 µmol but there were toxic effects above 600 µmol, indicating that adult flies were more resistant to selenium intoxication. In larvae, a when diphenyl diselenide was present above the toxic threshold there was increased... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Gene activation; Hsp83 gene; Selenium; Diphenyl diselenide. |
| Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572008000100022 |
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