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Relationship between uric acid levels and risk of chronic kidney disease in a retrospective cohort of Brazilian workers BJMBR
Chini,L.S.N.; Assis,L.I.S.; Lugon,J.R..
Uric acid (UA) levels are increased in patients with kidney dysfunction. We analyzed the association between asymptomatic hyperuricemia and new-onset chronic kidney disease (CKD). A retrospective cohort study was designed to collect data from employees of an energy generation and distribution company in the city of Rio de Janeiro, Brazil, who had undergone the company’s annual medical checkup from 2008 to 2014. People with ≤2 years of follow-up, with baseline estimated glomerular filtration rate (eGFR) <60 mL·min-1·(1.73 m2)-1 or with incomplete data were excluded. The endpoint was defined as eGFR <60 mL·min-1·(1.73 m2)-1 estimated through the chronic kidney disease epidemiology collaboration equation (CKD-EPI). The study included 1094 participants....
Tipo: Info:eu-repo/semantics/article Palavras-chave: Chronic kidney disease; Hyperuricemia; Glomerular filtration rate.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2017000900611
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Kinetics of acid-base parameters in conventional hemodialysis BJMBR
Lugon,J.R.; Pereira,G.R.M.; Strogoff-de-Matos,J.P.; Peixoto,A.J..
Details about the acid-base changes in hemodialysis are scarce in the literature but are potentially relevant to adequate management of patients. We addressed the acid-base kinetics during hemodialysis and throughout the interdialytic period in a cross-sectional study of adults undergoing conventional hemodialysis. Samples for blood gas analysis were obtained from the arterial limb of the arteriovenous fistula before the first session of the week (HD1), immediately at the end of HD1, and on sequential collections at 15, 30, 45, 60, and 120 min post-HD1. Additional blood samples were collected after ∼20 h following the end of the first dialysis and immediately prior to the initiation of the second dialysis of the week. Thirty adult patients were analyzed...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Hemodialysis; Renal replacement therapy; Kinetics; Adequacy of dialysis; Acid-base.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2019000100611
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Serum uric acid and disorders of glucose metabolism: the role of glycosuria BJMBR
Andrade,J.A.M.; Kang,H.C.; Greffin,S.; Garcia Rosa,M.L.; Lugon,J.R..
Hyperuricemia has been associated with hypertension, diabetes mellitus, and metabolic syndrome. We studied the association between hyperuricemia and glycemic status in a nonrandomized sample of primary care patients. This was a cross-sectional study of adults ≥20 years old who were members of a community-based health care program. Hyperuricemia was defined as a value >7.0 mg/dL for men and >6.0 mg/dL for women. The sample comprised 720 participants including controls (n=257) and patients who were hypertensive and euglycemic (n=118), prediabetic (n=222), or diabetic (n=123). The mean age was 42.4±12.5 years, 45% were male, and 30% were white. The prevalence of hyperuricemia increased from controls (3.9%) to euglycemic hypertension (7.6%) and...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Hyperuricemia; Glycosuria; Diabetes mellitus; Prediabetes.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2014001000917
Registros recuperados: 3
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