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| Shen,Xiaogang; Bai,Yifeng; Luo,Bin; Zhou,Xiaogang. |
| Abstract Background Growing evidence has supported that long non-coding RNAs (lncRNAs) could play vital roles in the development, progression, and prognosis of colorectal cancer (CRC). However, little is known about the clinical significance of BRAF-activated non-coding RNA (BANCR) in CRC. The aim of this study is to explore the clinical value of lncRNA BANCR in CRC patients. Methods The expression of lncRNA BANCR was measured in 106 CRC tissues and 65 adjacent normal tissues using the quantitative real-time PCR. Results The study showed that lncRNA BANCR was highly expressed in CRC tissues compared with adjacent normal tissues (P < 0.001). In addition, high expression of lncRNA BANCR was positively correlated with the lymph node metastasis (P... |
| Tipo: Journal article |
Palavras-chave: LncRNA; BANCR; Colorectal cancer; Lymph node metastasis; Prognosis. |
| Ano: 2017 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602017000100223 |
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| Dai,Xin; Zhou,Ling-Yu; Xu,Ting-Ting; Wang,Qiu-Yue; Luo,Bin; Li,Yan-Yu; Gu,Chen; Li,Shi-Ping; Wang,Ai-Qin; Wei,Wan-Hong; Yang,Sheng-Mei. |
| ABSTRACT Tannins are polyphenols that are present in various plants, and potentially contain antioxidant properties that promote reproduction in animals. This study investigated how tannic acid (TA) affects the reproductive parameters of male Brandt’s voles, Lasiopodomys brandtii (Radde, 1861). Specifically, the anti-oxidative level of serum, autophagy in the testis, and reproductive physiology were assessed in males treated with TA from the pubertal stage. Compared to the control, low dose TA enhanced relative testis and epididymis weight and sperm concentration in the epididymis, and significantly increased the level of serum superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px). mRNA levels of autophagy related genes LC3 and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antioxidative; Autophagy; Puberty; Reproduction. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-46702020000100319 |
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