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GAMBOA,JORGE; CACEDA,RICARDO; GAMBOA,ALFREDO; MONGE-C,CARLOS. |
Red blood cell carbonic anhydrase (CA) activity has not been studied in high altitude natives. Because CA is an intraerythocytic enzyme and high altitude natives are polycythemic, it is important to know if the activity of CA per red cell volume is different from that of their sea level counterparts. Blood was collected from healthy subjects living in Lima (150m) and from twelve subjects from Cerro de Pasco (4330m), and hematocrit and carbonic anhydrase activity were measured. As expected, the high altitude natives had significantly higher hematocrits than the sea level controls (p=0.0002). No difference in the CA activity per milliliter of red cells was found between the two populations. There was no correlation between the hematocrit and CA activity. |
Tipo: Journal article |
Palavras-chave: Carbonic anhydrase; Hypoxia; Polycythemia. |
Ano: 2000 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602000000300006 |
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OSTOJIC,HRVOJ; MONGE-C,CARLOS; CIFUENTES,VERONICA. |
Blood oxygen affinity and red blood cell properties were measured in three subspecies of genus Bufo: Bufo spinulosus limensis, collected at sea level and at an average day temperature of 20ºC; Bufo spinulosus trifolium, from 3100 m, average day temperature of 15ºC; and Bufo spinulosus flavolineatus, from 4100 m, average day temperature of 10ºC. Electrophoresis of the hemoglobin showed the same component in each of the three subspecies. At 20ºC the blood oxygen affinities (P50) showed small differences between Bufo spinulosus limensis and Bufo spinulosus trifolium, whereas the value for Bufo spinulosus flavolineatus was markedly lower. At 10ºC, the ambient temperature of Bufo spinulosus flavolineatus, the P50 was extremely low compared with the other two... |
Tipo: Journal article |
Palavras-chave: Adaptations; Altitude; Amphibians; Bufo spinulosus limensis; Bufo spinulosus trifolium; Bufo spinulosus flavolineatus; Hemoglobin affinity; Hematocrits; Oxygen binding; Toads. |
Ano: 2000 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602000000100007 |
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