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Nephroprotective activity of the enriched polyphenol extract of Euterpe edulis Martius BJPS
Cardoso,Priscylla Maria Martins; Mazuco,Renata Alves; Macedo,Lucas Soares Dazzi; Polese,Ariele Abreu Venturini; Barroso,Maria Eduarda de Souza; Baratella,Waléria Gramilich; Andrade,Tadeu Uggere de; Lenz,Dominik; Pereira,Thiago de Melo Costa; Endringer,Denise Coutinho.
Contrast-induced nephropathy (NIC) is directly related to increased morbidity and mortality, and its treatment and prevention might be achieved by the administration of antioxidant products. The juçara palmetto (Euterpe edulis Martius) has fruits rich in phenolic compounds, which are known for their antioxidant activity. This work aimed to evaluate the nephroprotective activity of E. edulis pulp in the NIC animal model. The collected fruits were pulped, their contents of polyphenols and anthocyanins were quantified, and their antioxidant activity were evaluated. The nephroprotective effects were determined based on iodine contrast induction and evaluated by biochemical and histological analyses. The results showed that E. edulis pulp was rich in...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Nephroprotection; Euterpe edulis Martius; Polyphenols; Anthocyanins; Antioxidant activity.
Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100522
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