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Effects of chronic exposure to hexavalent chromium in water on oxidative stress parameters in Wistar rats Biological Sciences
Machado, Aline Belem; Caprara, Juliana Foresti; Franceschi, Itiane Diehl de; Linden, Rafael; Berlese, Daiane Bolzan; Feksa, Luciane Rosa.
Hexavalent chromium [Cr (VI)] is a metal utilized in different industries and consequently disposed in the environment. It is a toxic substance and its reduction to trivalent Cr [Cr (III)] generates intermediates, which are responsible for the oxidation of molecules, and cause the oxidative stress. Therefore, the aim of this study was to evaluate if Cr (VI) could induce oxidative stress in Wistar rats. In this study, Wistar rats were chronically exposed to 25 and 50 ppm of potassium dichromate in drinking water for 30 days. The levels of Cr were evaluated in the blood and tissues (liver, kidneys, and lungs). Oxidative stress was determined in the liver, kidneys, and lungs and was evaluated by DFCH, TBA-RS and carbonyl test. Antioxidant enzymes were...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Bioquímica; Meio Ambiente; Contaminação metais pesados Antioxidant enzymes; Environmental contamination; Hexavalent chromium; Oxidative stress. Bioquímica.
Ano: 2019 URL: http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/43771
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