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	Provedor de dados J. Venom. Anim. Toxins incl. Trop. Dis. (1) Autor Machado,GF (1) Marinho,M (1) Monteiro,CMR (1) Oliveira-Júnior,IS (1) Peiró,JR (1) Palavra-chave IL-6 (1) Immunohistochemistry (1) Leptospirosis (1) Mice (1) TNF-α (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2008 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última TNF-α and IL-6 immunohistochemistry in rat renal tissue experimentaly infected with Leptospira interrogans serovar Canicola J. Venom. Anim. Toxins incl. Trop. Dis. Marinho,M; Monteiro,CMR; Peiró,JR; Machado,GF; Oliveira-Júnior,IS. Leptospirosis is a public health problem worldwide and its etiology remains unclear. Its pathogenesis involves a complex interaction between host and infecting microorganism. The inflammatory reaction that controls the infection process also underscores many pathophysiological events occurring in leptospirosis. We investigated the presence of tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) in renal tissues by immunohistochemical and histopathological examination in animals experimentally inoculated with Leptospira serovar Canicola. All the tests were carried out 2, 7, 14, 21 or 28 days after inoculation. Although TNF-α and IL-6 had been detected in tissues throughout the observation period, these cytokines appeared more intensely during the... Tipo: Info:eu-repo/semantics/article Palavras-chave: Leptospirosis; Immunohistochemistry; IL-6; TNF-α; Mice. Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992008000300012 Registros recuperados: 1 Primeira ... 1 ... Última

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