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Sabbatani,Sergio; Fiorino,Sirio; Manfredi,Roberto. |
After examining the most recent scientific evidences, which assessed the role of some malaria plasmodia that have monkeys as natural reservoirs, the authors focus their attention on Plasmodium knowlesi. The infective foci attributable to this last Plasmodium species have been identified during the last decade in Malaysia, in particular in the states of Sarawak and Sabah (Malaysian Borneo), and in the Pahang region (peninsular Malaysia). The significant relevance of molecular biology assays (polymerase chain reaction, or PCR, performed with specific primers for P. knowlesi), is underlined, since the traditional microscopic examination does not offer distinguishing features, especially when the differential diagnosis with Plasmodium malariae is of concern.... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Malaria parasites; Plasmodium knowlesi; Emerging plasmodia; Human health; Public health concerns. |
Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000300019 |
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Manfredi,Roberto; Sabbatani,Sergio; Calza,Leonardo. |
A patient with HIV infection developed the first episode of AIDS-defining opportunism (severe Candida albicans esophagitis) with an underlying CD4+ lymphocyte count of 1,025 cells/µL. After treatment with a highly active antiretroviral therapy (HAART), taken with insufficient compliance and leaving a residual viral load, our patient suffered from two relapses of esophageal candidiasis, which occurred three months and seven years later, when his CD4+ lymphocyte count was 930 and 439 cells/µL, respectively, and a viral load slightly above 10(4) copies/mL was still present. Also in the HAART era, Candida esophagitis remains one of the most common AIDS-defining diseases, but a presentation with a concurrent CD4+ count above 1,000 cells/µL remains a rare... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Esophageal candidiasis; HIV infection; CD4+ lymphocyte count; HIV viral load; Recurring opportunistic disease; Antiretroviral therapy; Negligible or absent immunodeficiency. |
Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702007000600016 |
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Manfredi,Roberto; Sabbatani,Sergio. |
Cat-scratch disease warrants extensive investigation, from an epidemiological, a diagnostic, but especially a therapeutic point of view. Two suggestive episodes of Bartonella henselae-caused cat-scratch disease are reported, and discussed in the light of the most recent literature evidence. The first case occurred in a 60-year-old man, thus suggesting that it is important to maintain an elevated level of suspicion for this disease in adults as well. Both episodes were characterized by a very prolonged and complicated disease course (with the involvement of three lymph node sets in the first case), a need for lymph-node drainage, and apparently negligible activity of many antimicrobial courses, with a very slow local cure. While specific culture and... |
Tipo: Info:eu-repo/semantics/report |
Palavras-chave: Adults; Antimicrobial chemotherapy; Bartonellosis; Bartonella henselae; Case reports; Children; Clinical presentation; Outcome; Treatment. |
Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702006000600012 |
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Manfredi,Roberto; Nanetti,Anna; Monte,Paola Dal; Calza,Leonardo. |
During recent years, a progressive emerging of tuberculosis occurred, related to the overall increased age of general population, primary and secondary (iatrogenic) immunodeficiencies, the availability of invasive procedures, surgical interventions and intensive care supports, bone marrow and solid organ transplantation, and especially the recent immigration flows of people often coming from areas endemic for tuberculosis, and living with evident social-economical disadvantages, and with a reduced access to health care facilities. Since January 2006, at our reference centre we followed 81 consecutive cases of pulmonary tuberculosis, with 65 of them which remained evaluable for the absence of extrapulmonary complications, and a continuative and effective... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Pulmonary tuberculosis; Microbiological assessment; Radiological assessment; Clinical-therapeutic issues; Selected antimicrobial treatments; Controlled observational study; Linezolid. |
Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702009000400012 |
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Sabbatani,Sergio; Baldi,Elena; Manfredi,Roberto; Chiodo,Francesco. |
BACKGROUND: The emergency regarding recent immigration waves into Italy makes continued healthcare monitoring of these populations necessary. METHODS: Through a survey of hospital admissions carried out during the last five years at the S. Orsola-Malpighi General Hospital of Bologna (Italy), all causes of admission of these subjects were evaluated, together with their correlates. Subsequently, we focused on admissions due to infectious diseases. All available data regarding foreign citizens admitted as inpatients or in Day-Hospital settings of our teaching hospital from January 1, 1999, to March 31, 2004, were assessed. Diagnosis-related group (DRG) features, and single discharge diagnoses, were also evaluated, and a further assessment of infectious... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Foreign citizens; Hospitalization; Immigration; Demographic and epidemiological features; Clinical diagnoses; Infectious diseases; Outcome. |
Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702006000200001 |
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Sabbatani,Sergio; Giuliani,Ruggero; Manfredi,Roberto. |
The elevated frequency of chronic hepatitis C virus (HCV) infection found among prison inmates, and the availability of improved pharmacological cure for this potentially life-threatening disorder, make investigations conducted in this somewhat neglected area very relevant, since only a few, open-label experiences have been reported till now. In the metropolitan prison of Bologna (Italy), HCV seroprevalence was found to be over 31% in 2003, so that a pilot feasibility study based on treatment with pegylated interferon plus ribavirin was initiated, after careful counseling carried out by a joint commission of health care personnel of the correctional facility and infectious diseases consultants. Thirty-nine patients were enrolled, and despite expected... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Chronic hepatitis C; Pegylated interferon; Ribavirin; Management; Inmates; Prison. |
Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702006000400012 |
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