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	Provedor de dados BABT (2) Autor Dias,Carla Roberta (2) Marczewski,Barbara (2) Moraes,Vanessa (2) Osso Junior,João Alberto (2) Barboza,Marycel Figols de (1) Palavra-chave Radiolabeling (2) Liquid Kit (1) Monoclonal antibodies (1) Nuclear medicine (1) Rhenium-188 HEDP (1) Technetium (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2005 (2) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Tc-99m direct radiolabeling of monoclonal antibody ior egf/r3: quality control and image studies in mice BABT Dias,Carla Roberta; Marczewski,Barbara; Moraes,Vanessa; Barboza,Marycel Figols de; Osso Junior,João Alberto. Monoclonal antibodies (Mabs) have been useful for immunoscintigraphic applications in clinical diagnosis since they were introduced in the practice of nuclear medicine. The ior egf/r3 (Centis, Cuba) is a murine monoclonal antibody against epidermal growth factor receptor (EGF-R) and has been widely used in the radioimmunodiagnosis of tumors of epithelial origin. Labeled with 99mTc, its main application in Nuclear Medicine is the follow up, detection and evaluation of tumor recurrences. The objective of this work is to describe the preparation of a lyophilized formulation (kit) for radiolabeling the Mab ior egf/r3 with 99mTc for immunoscintigraphic applications. Radiolabeling efficiency, effects on immunoreactivity, image studies and stability of the... Tipo: Info:eu-repo/semantics/article Palavras-chave: Radiolabeling; Technetium; Monoclonal antibodies; Nuclear medicine. Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000700004 Liquid kit for preparation of 188rhenium-etidronate BABT Marczewski,Barbara; Dias,Carla Roberta; Moraes,Vanessa; Osso Junior,João Alberto. The aim of this study was the preparation of a liquid kit for radiolabeling of 188Re-HEDP (hydroxyethylidene diphosphonate). 188Re was obtained from alumina based 188W/188Re generators. This paper reports the efficacy of a cold kit stored for more than two weeks, determined by the dependence of the radiolabeling yields of 188Re-HEDP on the incubation time, reducing agent concentration, the effects of concentration of ligand, the pH of the reaction and the temperature. The cold kits showed a good stability when carrie-free rhenium-188 was added in the reaction mixture. Tipo: Info:eu-repo/semantics/article Palavras-chave: Rhenium-188 HEDP; Liquid Kit; Radiolabeling. Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000700019 Registros recuperados: 2 Primeira ... 1 ... Última

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