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| Jacquot, Maude; Bisseux, Maxime; Abrial, David; Marsot, Maud; Ferquel, Elisabeth; Chapuis, Jean-louis; Vourc'H, Gwenael; Bailly, Xavier. |
| Lyme disease is a zoonosis caused by various species belonging to the Borrelia burgdorferi bacterial species complex. These pathogens are transmitted by ticks and infect multiple, taxonomically distinct, host species. From an epidemiological perspective, it is important to determine whether genetic variants within the species complex are able to spread freely through the whole host community or, instead, if certain variants are restricted to particular hosts. To this end, we characterized the genotypes of members of the B. burgdorferi species complex; the bacteria were isolated from more than two hundred individuals captured in the wild and belonging to three different rodent host species. For each individual, we used a high-throughput approach to amplify... |
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| Ano: 2014 |
URL: https://archimer.ifremer.fr/doc/00667/77888/80061.pdf |
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| Jacquot, Maude; Abrial, David; Gasqui, Patrick; Bord, Severine; Marsot, Maud; Masseglia, Sebastien; Pion, Angelique; Poux, Valerie; Zilliox, Laurence; Chapuis, Jean-louis; Vourc'H, Gwenael; Bailly, Xavier. |
| Many pathogens are maintained by multiple host species and involve multiple strains with potentially different phenotypic characteristics. Disentangling transmission patterns in such systems is often challenging, yet investigating how different host species contribute to transmission is crucial to properly assess and manage disease risk. We aim to reveal transmission cycles of bacteria within the Borrelia burgdorferi species complex, which include Lyme disease agents. We characterized Borrelia genotypes found in 488 infected Ixodes ricinus nymphs collected in the Senart Forest located near Paris (France). These genotypes were compared to those observed in three sympatric species of small mammals and network analyses reveal four independent transmission... |
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| Ano: 2016 |
URL: https://archimer.ifremer.fr/doc/00667/77885/80049.pdf |
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