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Disruptive Strategies for Removing Drug Discovery Bottlenecks Nature Precedings
Sean Ekins; Chris L. Waller; Mary P. Bradley; Antony J. Williams.
Drug Discovery is shifting focus from the industry to outside partners and in the process creating new bottlenecks, suggesting the need for a more disruptive overhaul. Technologies like high throughput screening (HTS) have moved to a larger number of academic and institutional laboratories in the US, with little apparent coordination or consideration of the outputs and creating a translational gap. While there have been collaborative public private partnerships in Europe to share pharmaceutical data, the USA has lagged behind. Sharing precompetitive computational models may be the next frontier to provide more confidence in the quality of the leads produced and attract investment. We suggest there needs to be an awareness of what research is going on in...
Tipo: Manuscript Palavras-chave: Chemistry; Pharmacology; Bioinformatics; Data Standards.
Ano: 2012 URL: http://precedings.nature.com/documents/6961/version/1
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