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	Provedor de dados BJMBR (2) Autor Matos,D.C.S. (2) Azeredo-Coutinho,R.B.G. (1) Homma,A. (1) Marcovistz,R. (1) Martins,R.M. (1) Mendonça,S.C.F. (1) Nery,J.A.C. (1) Neves,P.C.C. (1) Silva,A.M.V. (1) Valete-Rosalino,C.M. (1) Mais... Palavra-chave Antibody avidity (1) DTP-Hib vaccine (1) Haemophilus influenzae type b (1) Interferon-gamma (1) Interleukin-10 (1) Leishmania braziliensis (1) Lepromatous leprosy (1) Mucocutaneous leishmaniasis (1) Mycobacterium leprae (1) PRP immune response (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Info:eu-repo/semantics/other (1) Ano 2012 (1) 2009 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Interleukin-10-dependent down-regulation of interferon-gamma response to Leishmania by Mycobacterium leprae antigens during the clinical course of a coinfection BJMBR Azeredo-Coutinho,R.B.G.; Matos,D.C.S.; Nery,J.A.C.; Valete-Rosalino,C.M.; Mendonça,S.C.F.. We have described a case of a patient with an intriguing association of mucocutaneous leishmaniasis with lepromatous leprosy, two opposite polar forms of these spectral diseases. In the present follow-up study, we investigated the effect of the addition of Mycobacterium leprae antigens on interferon-gamma (IFN-γ) production in Leishmania antigen-stimulated cultures of peripheral blood mononuclear cells (PBMC) from this patient. For this purpose, PBMC cultures were stimulated with crude L. braziliensis and/or M. leprae whole-cell antigen extracts or with concanavalin A. In some experiments, neutralizing anti-human interleukin (IL)-10 antibodies were added to the cultures. IFN-γ and IL-10 levels in culture supernatants were measured by ELISA. During active... Tipo: Info:eu-repo/semantics/other Palavras-chave: Interferon-gamma; Interleukin-10; Mucocutaneous leishmaniasis; Lepromatous leprosy; Leishmania braziliensis; Mycobacterium leprae. Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000700010 Pattern of functional antibody activity against Haemophilus influenzae type b (Hib) in infants immunized with diphtheria-tetanus-pertussis/Hib Brazilian combination vaccine BJMBR Matos,D.C.S.; Silva,A.M.V.; Neves,P.C.C.; Martins,R.M.; Homma,A.; Marcovistz,R.. We evaluated the functional activity of Haemophilus influenzae B (Hib) antibodies elicited in a group of infants immunized with the diphtheria-tetanus-pertussis vaccine combined with an Hib vaccine produced totally in Brazil after technological transfer of Hib vaccine production from Glaxo SmithKline, Belgium. Blood samples from immunized infants (N = 985) were collected for the determination of Hib antibodies. Total Ig and IgM and IgG subclasses of antibodies against polyribosyl ribitol phosphate (PRP) were analyzed by ELISA. Almost all vaccinees (97.56%, 961/985) developed a strong anti-PRP IgG antibody response (≥1.0 μg/mL), while an anti-PRP IgM response was observed in 64.24% (634/985) of them (≥0.15 μg/mL). Only 18.88% (186/985) of the infants in the... Tipo: Info:eu-repo/semantics/article Palavras-chave: DTP-Hib vaccine; Haemophilus influenzae type b; Antibody avidity; PRP immune response. Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009001200020 Registros recuperados: 2 Primeira ... 1 ... Última

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