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Clinical correlates of pp65 antigenemia monitoring in the first months of post kidney transplant in patients undergoing universal prophylaxis or preemptive therapy BJID
Carvalho,Fabiana Rabe; Cosendey,Rachel Ingrid Juliboni; Souza,Cintia Fernandes; Medeiros,Thalia; Menezes,Paulo Alexandre; Silva,Andrea Alice; Almeida,Jorge Reis; Lugon,Jocemir Ronaldo.
Abstract Introduction: Human cytomegalovirus is a major cause of morbidity in kidney transplant patients. Objectives: We aimed to study viral replication and serological response in the first months post kidney transplant in patients undergoing universal prophylaxis or preemptive therapy and correlate the findings with the clinical course of Human cytomegalovirus infection. Patients and methods: Independent from the clinical strategy adopted for managing Human cytomegalovirus infection, prophylaxis versus preemptive therapy, the pp65 antigenemia assay and serological response were assessed on the day of transplantation, and then weekly during the first three months of post-transplant. Results: From the 32 transplant recipients, 16 were positive for...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cytomegalovirus; Pp65 antigenemia; Kidney transplant; Universal prophylaxis; Preemptive therapy.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702017000100051
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