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Melis, Blandine; Bocquene, Gilles; Raffin, Bernard. |
This report presents the state of art of endocrine disruption aspects in ecotoxicology. Some contaminants of the aquatic environment are able to mimic female fish hormones and thereby cause inappropriate feminisation of male fish. This feminisation involves artificial induction and emergence of ovotestis in male (oestrogenic disruption). Natural and synthetic oestrogenic hormones and several contaminants (alkylphenols, PCBs, phtalates and some pesticides) are already known to cause widespread feminisation of male. Two different types of analysis can be performed to detect oestrogenics effects. Immunochemical analysis of plasma (Enzyme-linked immunosorbent assay ELISA and radioimmuno assay RIA) shows that xenoestrogens induce vitellogenin and protein zona... |
Tipo: Text |
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Ano: 1999 |
URL: http://archimer.ifremer.fr/doc/00076/18758/16328.pdf |
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