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| Cleff,Marlete Brum; Meinerz,Ana Raquel; Xavier,Melissa; Schuch,Luiz Filipe; Meireles,Mário Carlos Araújo; Rodrigues,Maria Regina Alves; Mello,João Roberto Braga de. |
| The aim of this study was to evaluate the in vitro activity of the essential oil extracted from Origanum vulgare against sixteen Candida species isolates. Standard strains tested comprised C. albicans (ATCC strains 44858, 4053, 18804 and 3691), C. parapsilosis (ATCC 22019), C. krusei (ATCC 34135), C. lusitaniae (ATCC 34449) and C. dubliniensis (ATCC MY646). Six Candida albicans isolates from the vaginal mucous membrane of female dogs, one isolate from the cutaneous tegument of a dog and one isolate of a capuchin monkey were tested in parallel. A broth microdilution technique (CLSI) was used, and the inoculum concentration was adjusted to 5 x 10(6) CFU mL-1. The essential oil was obtained by hydrodistillation in a Clevenger apparatus and analyzed by gas... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Candida; Origanum vulgare; Essential oil; In vitro. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822010000100018 |
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| Nascente,Patrícia da Silva; Meinerz,Ana Raquel Mano; Faria,Renata Osório de; Schuch,Luiz Filipe Damé; Meireles,Mário Carlos Araújo; Mello,João Roberto Braga de. |
| Thiabendazole, classified as antiparasitic and also used as an antifungal drug, can be found as otological solution indicated for treatment of parasitic and fungal external otitis in small animals. Malassezia pachydermatis is a yeast recognized as a normal inhabitant on the skin and mucous membranes of dogs and cats. However, it is considered an opportunistic agent that causes external otitis and dermatitis in these animals. The aim of this study was to evaluate the in vitro effect of thiabendazole against 51 isolates of M. pachydermatis using the CLSI Broth Microdilution method that has been adapted for this yeast species (NCCLS, 2002). Based on this test, the Minimum Inhibitory Concentrations (MIC) of thiabendazol was calculated. Subsequently, the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Malassezia pachydermatis; Minimum Inhibitory Concentration; Thiabendazole. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822009000200002 |
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| Santin,Rosema; Mattei,Antonella Souza; Waller,Stefanie Bressan; Madrid,Isabel Martins; Cleff,Marlete Brum; Xavier,Melissa Orzechowski; Nobre,Márcia de Oliveira; Nascente,Patrícia da Silva; Mello,João Roberto Braga de; Meireles,Mário Carlos Araújo. |
| The oral microbiota of humans and animals is made up of a wide variety of yeasts and bacteria, but microbiota of dogs is not totally described. Although such identification is an important step to establish the etiopathogenesis and adequate therapy for the periodontal disease The aim of this study was to evaluate and correlate oral alterations with the presence of yeasts in oral cavity of female dogs. After clinical evaluation samples from healthy and from dogs with oral diseases were obtained from three different oral sites by swabs, curettes, millimeter periodontal probes and HA membrane tip in cellulose ester. Yeast identification was performed through macroscopic and microscopic colony features and biochemical tests. Dental calculus was the most... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Oral microbiota; Yeasts; M. pachydermatis; Candida spp.; Halitosis. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822013000100020 |
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| Waller,Stefanie Bressan; Madrid,Isabel Martins; Faria,Renata Osório de; Cleff,Marlete Brum; Mello,João Roberto Braga de; Meireles,Mário Carlos Araújo. |
| ABSTRACT Cases of sporotrichosis in humans and animals without satisfactory clinical response have increased, a warning sign of strains resistant to conventional antifungal agents. The urgent search for alternative therapies was an incentive for research on medicinal plants with anti-Sporothrix spp. properties. A bibliographic survey was performed based on scientific papers about in vitro and in vivo antifungal activity of essential oils and extracts of plants in differents solvents against the fungal of the Sporothrix schenckii complex. The study methodology consisted of a literature review in Google Scholar, Science Direct, Pubmed, Bireme and Springer link with papers from 1986 to 2015. We found 141 species of plants that were investigated, of which 100... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Sporothrix schenckii complex; Antifungals; Combretaceae/pharmacognosy; Asteraceae/pharmacognosy; Lamiaceae/pharmacognosy; Medicinal plants/antifungal activity. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502016000200221 |
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| Hollenbach,Clarissa Boemler; Stedile,Rafael; Mello,Fabíola Peixoto da Silva; Bing,Rafaela Scheer; Rosa,Patrícia Pisoni da; Rodrigues,Maria Regina Alves; Mello,Fernanda Bastos de; Zanette,Régis Adriel; Mello,João Roberto Braga de. |
| ABSTRACT: Despite the increasing use of oregano ( Origanum vulgare L.) essential oil for therapeutic purposes, pre- and postnatal development of animals offspring exposed to this oil has not yet been evaluated. In line with previous concerns of genotoxicity, in this study adult rats were exposed to different doses of oregano essential oil (3, 9 and 27% vol/vol) during pre-mating, mating, gestation and lactation. Prenatal screening included fetal development and uterine inspection, where the reproductive rate of females such as breeding, pregnancy, delivery, viability and post-implantation loss rate were measured. Postnatal evaluation of rat offspring included motor development, neuroendocrine and behavioral assessment. Body weight of rat dams and signs of... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Oregano; Reproductive toxicity; Progeny; Reproduction; Rats. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782017000100552 |
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| Mello,João Roberto Braga de; Langeloh,Augusto; Habermehl,Gerhard; Krebs,Hans; Bastos,Fernanda; Alvares,Fernanda. |
| Os efeitos da administração oral dos extratos aquoso (NvH2O), metanólico (NvmeOH), butanólico (Nvbut) e hexano (Nvhex), obtidos, seqüencialmente, de 500g de Nierembergia veitchii (planta seca), foram comparados aos obtidos com vitamina D3 (2,5mg.kg-1) e aos de um grupo controle (solução fisiológica - SF), quando administrados, durante todo o período de gestação (21 dias), a ratas albinas Wistar. A redução do ganho de peso foi evidente nas fêmeas tratadas com Nvhex, Nvbut e vitamina D3. Nesses grupos, houve redução do número de implantes uterinos (9,3 ± 1,4; 9,6 + 1,4 e 8,4 ± 1,4), quando comparados com o controle (SF) (11,2 ± 0,4). Essa redução também foi observada no número de filhotes por ninhada (8,1 ± 1,3; 9,0 ± 1,5; 5,1 ± 1,7 e 10,3 ± 0,6), e na massa... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Plantas calcinogênicas; Nierembergia veitchii; Vitamina D3; Infertilidade; Teratogenia. |
| Ano: 2000 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782000000300006 |
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