|
|
|
|
|
| Pinto,MCL; Melo,MB; Cruz,ML; Verçosa Junior,D; Melo,MM. |
| Accidental envenomation caused by Tityus serrulatus scorpions is very common in Brazil and may result in serious cardiorespiratory alterations that are frequently fatal to children. In the present study, the effects of T. serrulatus venom on the cardiorespiratory system of recently weaned male Wistar rats were evaluated. Fifteen animals were distributed into three groups (n = 5). The control group A received 400 μL ultrapure water by subcutaneous injection, while the experimental groups B and C were injected with scorpion venom (100 and 450 μg, respectively, in 400 μL water). Electrocardiogram (ECG) traces were obtained prior to the experiment, at five-minute intervals up to 30 minutes after treatment. At 40 minutes after envenomation, the animals had... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Tityus serrulatus; Rats; Electrocardiography; CK; CK-MB; Troponin; Pulmonary hemorrhages. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992010000200008 |
| |
|
|
| Borboleta,LR; Silva,EF; Oliveira,MS; Michel,AFRM; Ferraz,VP; Leite,RC; Melo,MM. |
| Clinical and laboratory changes were evaluated in rabbits after intoxication by Amorimia rigida, a plant that causes sudden death. Nine New Zealand male rabbits, averaging 3.54 kg, were categorized into three groups (n = 3) and received, for eight consecutive days, the equivalent of 30 g/kg dry matter of A. rigida water-soluble (SG) and water-insoluble (IG) extracts via nasoesophageal route. The control group received water. There were no alterations in creatine kinase enzyme (CK), CK myocardial fraction (CKMB) or troponine I (cTnI). None of the animals had clinical or electrocardiographic (conventional and Holter) alterations. There were progressive decreases in the left ventricular ejection fraction and systolic fractional shortening. Doppler... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Toxic plant; Amorimia rigida; Cardiac muscle profile; Electrocardiography; Echocardiography; Rabbit. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992012000300007 |
| |
|
|
| Gadelha,ICN; Lima,MA; Melo,MM; Soto-Blanco,B. |
| ABSTRACT Gossypol, a phenolic compound produced by the pigment glands of cotton, is known to affect male reproduction. In females, exposure to gossypol has been associated with interference with the estrous cycle and embryo development. In laying hens fed cottonseed, gossypol was found to reduce egg production and weight and to cause discoloration of the egg yolk and/or albumen. It is probable that gossypol directly affects ovarian follicles, but this has not been confirmed experimentally yet. Thus, the aim of the present study was to determine if gossypol affected cultivated ovarian follicles of the chicken. Ovarian follicles of adult female chickens were cultivated with different concentrations of gossypol (0, 5, 10 and 20 μg/mL) and classified according... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cottonseed; Female reproduction; Gossypol; Ovaries; Reproductive toxicology. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2016000300505 |
| |
|
|
|
