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| Rodrigues,D.F.; Mendes,F.F.; Melo,R.M.; Menezes,L.B.; Guimarães,L.L.B.; Silva,A.S.; Rammazzina Filho,W.A.; Moraes,A.M.; Paulo,N.M.. |
| ABSTRACT The aim of this study was to characterize the tissue reactions triggered by the polypropylene mesh coated with chitosan and polyethylene glycol film, and if it’s able to prevent the formation of peritoneal adhesions. Defects in the abdominal wall of rats were induced and polypropylene meshes coated with chitosan/polyethylene glycol (CPEG group, n= 12) and uncoated (PP control group, n= 12) were implanted. On the fourth and forty-fifth postoperative day the formation of adhesion and the tissue reaction to the biomaterial was evaluated through histological and histochemical analysis. The area (P= 0.01) and severity (P= 0.002) of the adhesion was significatively less in the CPEG group. On the fourth day the foreign body reaction was less intense in... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Foreign-body reaction; Hernia; Peritoneal adhesions; Prosthesis; Surgical mesh. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352019000401198 |
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