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| Mercurio,Daiane Garcia; Calixto,Lívia Salomão; Campos,Patrícia Maria Berardo Gonçalves Maia. |
| Considering the importance of an adequate composition of the formulation in the development of stable, safe and effective cosmetic products, experimental design techniques are tools that can optimize the formulation development process. The objective of this study was to develop topical formulations using the Box-Behnken design with response surface methodology and evaluate its physical, sensory and moisturizing properties. The experimental design used in the first step allowed to identify and to quantify the influence of raw materials, as well as the interaction between them. In the second step, the analysis identified the influence of soy lecithin, the phytantriol and capric acid triglyceride and caprylic on the consistency index, stickiness and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Emulsions; Formulation; Stability; Skin barrier; Experimental design. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100624 |
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| Tadini,Kassandra Azevedo; Mercurio,Daiane Garcia; Campos,Patrícia Maria Berardo Gonçalves Maia. |
| abstract Acetyl hexapeptide-3 has been used in anti-aging topical formulations aimed at improving skin appearance. However, few basic studies address its effects on epidermis and dermis, when vehiculated in topical formulations. Thus, the objective of this study was to determine the clinical efficacy of acetyl hexapeptide-3 using biophysical techniques. For this purpose, formulations with and without acetyl hexapeptide-3 were applied to the ventral forearm and the face area of forty female volunteers. Skin conditions were evaluated after 2 and 4-week long daily applications, by analyzing the stratum corneum water content and the skin mechanical properties, using three instruments, the Corneometer(r) CM 825, CutometerSEM 575 and ReviscometerRV600. All... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Acetyl hexapeptide-3/use in cosmetic formulations; Acetyl hexapeptide-3/clinical efficacy; Biophysical techniques; Anti-aging/cosmetics; Clinical efficacy; Cosmetics.. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000400901 |
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