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Daily blood pressure profile in Cushing's syndrome before and after surgery BJMBR
Kreze,A.; Mikulecky,M..
No significant difference has been demonstrated in the altered circadian blood pressure pattern between the pituitary-dependent and adrenal forms of Cushing's syndrome before surgery. The effect of therapy, however, proved to be different. The mesor was normalized in the pituitary-dependent Cushing's syndrome more conspicuously for systolic than for diastolic blood pressure. In Cushing's syndrome due to adrenal adenoma, systolic and diastolic blood pressure mesors have been even significantly "overnormalized" after treatment, being 11 to 27 and 2 to 13 mmHg (95% confidence) lower than corresponding mesors in controls. There was no difference between forms in the effect of treatment on blood pressure amplitudes, which remained significantly lower than in...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cushing's syndrome; Pituitary-dependent Cushing's syndrome; Cushing's syndrome due to adrenal adenoma; Blood pressure; Circadian rhythm; Surgery.
Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999001000004
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Risk factors for glucose intolerance in active acromegaly BJMBR
Kreze,A.; Kreze-Spirova,E.; Mikulecky,M..
In the present retrospective study we determined the frequency of glucose intolerance in active untreated acromegaly, and searched for risk factors possibly supporting the emergence of the diabetic condition. Among 43 patients, 8 (19%; 95% CI: 8-33%) had diabetes mellitus and 2 (5%; 1-16%) impaired glucose tolerance. No impaired fasting glycemia was demonstrable. The frequency of diabetes was on average 4.5 times higher than in the general Slovak population. Ten factors suspected to support progression to glucose intolerance were studied by comparing the frequency of glucose intolerance between patients with present and absent risk factors. A family history of diabetes and arterial hypertension proved to have a significant promoting effect (P<0.05,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Acromegaly; Diabetes mellitus; Impaired glucose tolerance; Impaired fasting glycemia; Risk factors; Inferential statistics.
Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001001100009
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Daily birth numbers in Passo Fundo, South Brazil, 1997-1999: trends and periodicities BJMBR
Mikulecky,M.; Lisboa,H.R.K..
Between October 6, 1997 and April 30, 1999, 5011 births (mean: 8.76 per day) were registered in the city of Passo Fundo, South Brazil. The sequence of 572 daily birth numbers was not random (iteration test). Neyman distribution (m = ¥) showed the best fit. Clusters of days with higher birth numbers alternated with days with low numbers of births. Periodogram analysis revealed a significant periodicity of 6.98 days. The cosinor regression, testing 10 a priori supposed period lengths, found significant seasonality peaking in August-September and significantly highest birth numbers on Thursdays. Among the lunar and solar rotation cycles, the tropic lunar cycle and its 4th harmonic were most pronounced, in agreement with results concerning natality in Germany...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Births; South Brazil; Periodogram; Cosinor; Seasonality; Weekly rhythm; Multiseptans; Cosmogeophysical-biomedical parallelism; Solar and lunar cycles.
Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002000800017
Registros recuperados: 3
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