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| Carvalho,Bráulio Matias de; Monteiro,André Jalles; Pires Neto,Roberto da Justa; Grangeiro,Thalles Barbosa; Frota,Cristiane Cunha. |
| Infection with both Human Immunodeficiency Virus (HIV) and Mycobacterium tuberculosis is currently the world's leading cause of death due to infectious agents. We evaluated factors related to the development of tuberculosis (TB) in HIV-infected patients who were being treated at an infectious diseases hospital in Fortaleza, Ceará, Brazil. From January 2004 to December 2005, we made an epidemiological study through the analysis of the medical records of 171 patients, who were diagnosed as having both HIV and tuberculosis. Among these co-infected patients, most (81%, p=0.0006) were male. Co-infection was more frequent (87.8%) among patients over 40 years of age and those with lower educational levels (less than eight years of schooling). Forty-one percent of... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: HIV; Mycobacterium tuberculosis; HIV/TB co-infection; Risk factors; AIDS. |
| Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000400005 |
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| Brilhante,Raimunda Sâmia Nogueira; Caetano,Érica Pacheco; Riello,Giovanna Barbosa; Guedes,Glaucia Morgana de Melo; Castelo-Branco,Débora de Souza Collares Maia; Fechine,Maria Auxiliadora Bezerra; Oliveira,Jonathas Sales de; Camargo,Zoilo Pires de; Mesquita,Jacó Ricarte Lima de; Monteiro,André Jalles; Cordeiro,Rossana de Aguiar; Rocha,Marcos Fábio Gadelha; Sidrim,José Júlio Costa. |
| Abstract Recent studies have shown that some drugs that are not routinely used to treat fungal infections have antifungal activity, such as protease inhibitor antiretroviral drugs. This study investigated the in vitro susceptibility of Histoplasma capsulatum var. capsulatum to saquinavir and ritonavir, and its combination with the antifungal itraconazole. The susceptibility assay was performed according to Clinical and Laboratory Standards Institute guidelines. All strains were inhibited by the protease inhibitor antiretroviral drugs. Saquinavir showed minimum inhibitory concentrations ranging from 0.125 to 1 μg mL−1 for both phases, and ritonavir presented minimum inhibitory concentrations ranging from 0.0312 to 4 μg mL−1and from 0.0625 to 1 μg mL−1 for... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Histoplasma capsulatum; Saquinavir; Ritonavir; Itraconazole. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000200155 |
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| Fé,Mariana Mota Moura; Monteiro,André Jalles; Moura,Fernanda Edna Araújo. |
| Little information on the epidemiology and clinical characteristics of human parainfluenza virus (HPIV) infections, especially in children from tropical countries, has been published. The aim of this study was to determine the frequency of HPIV infections in children attended at a large hospital in Fortaleza in Northeast Brazil, and describe seasonal patterns, clinical and epidemiological characteristics of these infections. From January 2001 to December 2006, a total of 3070 nasopharyngeal aspirates collected from children were screened by indirect immunofluorescence for human parainfluenza viruses 1, 2, and 3 (HPIV-1, 2 and 3) and other respiratory viruses. Viral antigens were identified in 933 samples and HPIV in 117. The frequency of HPIV-3, HPIV-1 and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Acute respiratory infections; Parainfluenza virus; Epidemiology; Brazil. |
| Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000300006 |
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| Brilhante,Raimunda Sâmia Nogueira; Caetano,Érica Pacheco; Lima,Rita Amanda Chaves de; Marques,Francisca Jakelyne de Farias; Castelo-Branco,Débora de Souza Collares Maia; Melo,Charlline Vládia Silva de; Guedes,Glaucia Morgana de Melo; Oliveira,Jonathas Sales de; Camargo,Zoilo Pires de; Moreira,José Luciano Bezerra; Monteiro,André Jalles; Bandeira,Tereza de Jesus Pinheiro Gomes; Cordeiro,Rossana de Aguiar; Rocha,Marcos Fábio Gadelha; Sidrim,José Júlio Costa. |
| Abstract This study aimed to evaluate the in vitro antifungal activity of terpinen-4-ol, tyrosol, and β-lapachone against strains of Coccidioides posadasii in filamentous phase (n = 22) and Histoplasma capsulatum in both filamentous (n = 40) and yeast phases (n = 13), using the broth dilution methods as described by the Clinical and Laboratory Standards Institute, to determine the minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) of these compounds. The mechanisms of action of these compounds were also investigated by analyzing their effect on cell membrane permeability and ergosterol synthesis. The MIC and MFCf these compounds against C. posadasii, mycelial H. capsulatum, and yeast-like H. capsulatum, were in the following... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Dimorphic fungi; Terpinen-4-ol; Tyrosol; Β-Lapachone; Inhibitory effect. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822016000400917 |
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| Amóra,Sthenia Santos Albano; Santos,Maria José Paes; Alves,Nilza Dutra; Costa,Sylvio Celso Gonçalves da; Calabrese,Kátia da Silva; Monteiro,André Jalles; Rocha,Marcos Fábio Gadelha. |
| O presente estudo objetivou descrever alguns fatores relacionados à positividade de cães para leishmaniose visceral, em área endêmica do Estado do Rio Grande do Norte. Foram analisados 198 cães, dos quais 62 foram recrutados de propriedades rurais e 136 de residências urbanas. O diagnóstico foi realizado através dos testes de imunofluorescência indireta e imunoadsorção enzimática. Dos cães analisados, 45% dos positivos eram provenientes da área rural e 35% da área urbana. Analisando a função dos animais, a prevalência foi de 50% dos cães de guarda nas áreas rural e de 43% na área urbana. Quanto aos cães que tinham contato com outros cães de origem rural ou urbana, a prevalência observada de foi 54% e 32%, respectivamente. No que se refere ao sexo, as... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Leishmaniose visceral; Cão; Sorodiagnóstico e fatores de risco. |
| Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782006000600029 |
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| Brilhante,Raimunda Sâmia Nogueira; Paiva,Manoel de Araújo Neto; Sampaio,Célia Maria de Souza; Teixeira,Carlos Eduardo Cordeiro; Ribeiro,Joyce Fonteles; Castelo-Branco,Débora de Souza Collares Maia; Bandeira,Tereza de Jesus Pinheiro Gomes; Monteiro,André Jalles; Cordeiro,Rossana de Aguiar; Sidrim,José Júlio Costa; Monteiro,Frederico Ozanan Barros; Moreira,José Luciano Bezerra; Rocha,Marcos Fábio Gadelha. |
| This study aimed to evaluate the role of the Amazon River prawn, Macrobrachium amazonicum, as carrier of Candida spp., by analyzing the correlation between Candida spp. from these prawns and their environment (surface water and sediment), through M13-PCR fingerprinting and RAPD-PCR. For this purpose, 27 strains of Candida spp. were evaluated. These strains were recovered from the gastrointestinal tract of adult M. amazonicum (7/27) from Catú Lake, Ceará State, Brazil and from the aquatic environment (surface water and sediment) of this lake (20/27). Molecular comparison between the strains from prawns and the aquatic environment was conducted by M13-PCR fingerprinting and RAPD-PCR, utilizing the primers M13 and OPQ16, respectively. The molecular analysis... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Macrobrachium amazonicum prawn environmental sentinel Candida spp. pollution; Monitoring. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782014001102029 |
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