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| Havt,Alexandre; Assreuy,Ana Maria Sampaio; Nascimento,Nilberto Robson Falcão do; Fonteles,Manassés Claudino; Pereira,Lívia de Paula; Monteiro,Sandra Maria Nunes; Barbosa,Paulo Sergio Ferreira; Nascimento,Kyria Santiago do; Cavada,Benildo Sousa; Martins,Alice Maria Costa; Monteiro,Helena Serra Azul. |
| Lectins have been described as glycoproteins that reversibly and specifically bind to carbohydrates. Legume lectins isolated from the subtribe Diocleinae (Canavalia, Dioclea andCratylia) are structurally homologous with respect to their primary structures. The Diocleinae lectins of Canavalia brasiliensis, Dioclea guianensis andCanavalia ensiformis have been shown to distinctly alter physiological parameters in isolated rat kidneys. Thus, the aim of this study was to investigate the effect of Cratylia floribunda lectin (CFL) on renal hemodynamics and ion transport in rats. In isolated perfused kidneys, CFL (10 mg/mL, n=5) increased RPP, RVR and decreased %TK+, but did not change urinary flow, glomerular filtration rate, sodium or chloride tubular transport.... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Plant lectin; Amiloride; Cratylia floribunda/lectina/renal hemodynamics; Renal hemodynamics; Ion-transport. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000300755 |
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