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Morais,Sabrina Kelly Reis de; Silva,Suniá Gomes; Portela,Cíntia Nicácio; Nunomura,Sergio Massayoshi; Quignard,Etienne Louis Jacques; Pohlit,Adrian Martin. |
Tabebuia incana A.H. Gentry (Bignoniaceae) is a tree from the Brazilian Amazon having medicinal uses and is one several Tabebuia spp. known as pau d'arco or palo de arco in this region. Fractionation of the bark ethanolic extract afforded a mixture of 5 and 8-hydroxy-2-(1-hydroxyethyl)naphtho[2,3-b]furan-4,9-diones (1 and 2, respectively) identified on the basis of nuclear magnetic resonance (NMR), infrared (IR) and mass (MS) spectra, whose in vitro antimalarial and antitumor activity have been shown previously. This is the first study on T. incana bark, and 2 are described in this species for the first time. Also, high performance liquid chromatography (HPLC) analysis of T. incana bark tea revealed the presence of the 1 + 2 mixture peak corresponding to a... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Artemia franciscana Leach 5-hydroxy-2-(1-hydroxyethyl)naphtho[2; 3-b]furan-4; 9-dione; 8-hydroxy-2-(1-hydroxyethyl)naphtho[2; 3-b]furan-4; 9-dione. |
Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672007000100011 |
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Pohlit,Adrian Martin; Quinard,Etienne Louis Jacques; Nunomura,Sergio Massayoshi; Tadei,Wanderli Pedro; Hidalgo,Ari de Freitas; Pinto,Ana Cristina da Silva; Santos,Elba Vieira Mustafa dos; Morais,Sabrina Kelly Reis de; Saraiva,Rita De Cássia Guedes; Ming,Lin Chau; Alecrim,Alexandre Mascarenhas; Ferraz,Alfeu de Barros; Pedroso,Andreza Cristiana da Silva; Diniz,Elisangela Vieira; Finney,Ellen Kathryn; Gomes,Erika de Oliveira; Dias,Hercules Bezerra; Souza,Katiuscia dos Santos de; Oliveira,Laura Cristina Pereira de; Don,Luciana de Castro; Queiroz,Maria Mireide Andrade; Henrique,Marycleuma Campos; Santos,Mirian dos; Lacerda Júnior,Orivaldo da Silva; Pinto,Patrícia de Souza; Silva,Suniá Gomes; Graça,Yara Rodrigues. |
Ethanol, methanol and water extracts representing mostly native plant species found in the Amazon region were prepared, respectively, by maceration, continuous liquid-solid extraction and infusion, followed by evaporation and freeze-drying. The freeze-dried extracts were tested for lethality toward Aedes aegypti larvae at test concentrations of 500 mg / mL. In general, methanol extracts exhibited the greatest larvicidal activity. The following 7 methanol extracts of (the parts of) the indicated plant species were the most active, resulting in 100% mortality in A. aegypti larvae: Tapura amazonica Poepp. (root), Piper aduncum L. (leaf and root), P. tuberculatum Jacq. (leaf, fruit and branch). and Simaba polyphylla (Cavalcante) W.W. Thomas (branch). |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Larvicide; Aedes aegypti; Tapura; Piper; Simaba; Amazonia. |
Ano: 2004 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672004000100012 |
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