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Concomitant stress potentiates the preference for, and consumption of, ethanol induced by chronic pre-exposure to ethanol BJMBR
Morais-Silva,G.; Fernandes-Santos,J.; Moreira-Silva,D.; Marin,M.T..
Ethanol abuse is linked to several acute and chronic injuries that can lead to health problems. Ethanol addiction is one of the most severe diseases linked to the abuse of this drug. Symptoms of ethanol addiction include compulsive substance intake and withdrawal syndrome. Stress exposure has an important role in addictive behavior for many drugs of abuse (including ethanol), but the consequences of stress and ethanol in the organism when these factors are concomitant results in a complex interaction. We investigated the effects of concomitant, chronic administration of ethanol and stress exposure on the withdrawal and consumption of, as well as the preference for, ethanol in mice. Male Swiss mice (30–35 g, 8-10 per group) were exposed to an ethanol liquid...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Ethanol; Addiction; Stress; Free-bottle choice; Withdrawal.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000100606
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