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| Silva,Aline Teixeira Maciel e; Magalhães,Cássia Gonçalves; Duarte,Lucienir Pains; Mussel,Wagner da Nova; Ruiz,Ana Lucia Tasca Gois; Shiozawa,Larissa; Carvalho,João Ernesto de; Trindade,Izabel Cristina; Vieira Filho,Sidney Augusto. |
| ABSTRACT The triterpene lupeol (1) and some of its esters are secondary metabolites produced by species of Celastraceae family, which have being associated with cytotoxic activity. We report herein the isolation of 1, the semi-synthesis of eight lupeol esters and the evaluation of their in vitro activity against nine strains of cancer cells. The reaction of carboxylic acids with 1 and DIC/DMAP was used to obtain lupeol stearate (2), lupeol palmitate (3) lupeol miristate (4), and the new esters lupeol laurate (5), lupeol caprate (6), lupeol caprilate (7), lupeol caproate (8) and lupeol 3’,4’-dimethoxybenzoate (9), with high yields. Compounds 1-9 were identified using FT-IR, 1H, 13C-NMR, CHN analysis and XRD data and were tested in vitro for proliferation of... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Lupeol/in vitro evaluation; Lupeol ester; K-562 cells; XRD method; Antiproliferative effect.. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502017000300621 |
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| Ribeiro,Fabiana Rodrigues; Egreja Filho,Fernando Barboza; Fabris,José Domingos; Mussel,Wagner da Nova; Novais,Roberto Ferreira. |
| The industrial refining of kaolin involves the removal of iron oxides and hydroxides along with other impurities that cause discoloration of the final product and depreciate its commercial value, particularly undesirable if destined to the paper industry. The chemical leaching in the industrial processing requires treatments with sodium hyposulfite, metallic zinc, or sulfuric and phosphoric acids, in order to reduce, dissolve and remove ferruginous compounds. To mitigate the environmental impact, the acidic effluent from the leaching process must be neutralized, usually with calcium oxide. The resulting solid residue contains phosphorous, zinc, and calcium, among other essential nutrients for plant growth, suggesting its use as a macro and micronutrient... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Industrial residue; Fertilizer; Kaolin refining. |
| Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-06832007000500011 |
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