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	Provedor de dados Anais da ABC (AABC) (2) Autor NEVES,MARIA G.P.M.S. (2) CAVALEIRO,JOSÉ A.S. (1) DIAS,CRISTINA J. (1) FARDILHA,MARGARIDA (1) FAUSTINO,MARIA AMPARO F. (1) GAMELAS,SARA (1) GOMES,ANA T.P.C. (1) MESQUITA,MARIANA Q. (1) Mais... Palavra-chave Cancer (1) Chlorins (1) Drug delivery (1) Gold nanoparticles (1) Liposomes (1) Photodynamic Therapy (1) Photodynamic therapy (1) Polymeric micelles (1) Porphyrins (1) Related macrocycles (1) Silica nanoparticles (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2018 (2) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Cancer, Photodynamic Therapy and Porphyrin-Type Derivatives Anais da ABC (AABC) GOMES,ANA T.P.C.; NEVES,MARIA G.P.M.S.; CAVALEIRO,JOSÉ A.S.. ABSTRACT This review has two parts. The first one gives an approach to interdisciplinary studies against cancer carried out by many scientists using porphyrin-type substrates as photosensitizers in PDT. Intensive studies were performed for almost six decades. The successes really started in 1993 with the first formulation patented under the trade name Photofrin, which was immediately approved in several countries to treat certain types of cancer. Photofrin is still used although certain negative features soon became well known. That has motivated the search for better new photosensitizers. Several ones were developed, evaluated and a few of them had clinical approval. This group includes porphyrin derivatives and pro-drugs (aminolevulinic acid and its... Tipo: Info:eu-repo/semantics/article Palavras-chave: Cancer; Photodynamic Therapy; Porphyrins; Chlorins; Related macrocycles. Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000300993 An insight on the role of photosensitizer nanocarriers for Photodynamic Therapy Anais da ABC (AABC) MESQUITA,MARIANA Q.; DIAS,CRISTINA J.; GAMELAS,SARA; FARDILHA,MARGARIDA; NEVES,MARIA G.P.M.S.; FAUSTINO,MARIA AMPARO F.. ABSTRACT Photodynamic therapy (PDT) is a modality of cancer treatment in which tumor cells are destroyed by reactive oxygen species (ROS) produced by photosensitizers following its activation with visible or near infrared light. The PDT success is dependent on different factors namely on the efficiency of the photosensitizer deliver and targeting ability. In this review a special attention will be given to the role of some drug delivery systems to improve the efficiency of tetrapyrrolic photosensitizers to this type of treatment. Tipo: Info:eu-repo/semantics/article Palavras-chave: Photodynamic therapy; Drug delivery; Liposomes; Silica nanoparticles; Gold nanoparticles; Polymeric micelles. Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000301101 Registros recuperados: 2 Primeira ... 1 ... Última

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